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Top 10 food allergy stories of 2025

December 29, 2025
3 min read
Fact checked byKristen Dowd

The first documented alpha-gal syndrome fatality from mammalian meat dominated our most popular food allergy coverage in 2025.

Perspective from Purvi Parikh, MD

Other top stories focused on a new protocol that resulted in two toddlers who had peanut allergy during infancy being able to safely consume peanuts and the psychosocial burden children with food allergy face.

Lone star tick
As the prevalence of the lone star tick continues to grow, better awareness of the symptoms of alpha-gal syndrome may prevent future tragedies. Image: Adobe Stock

Check out the list below for our most-read stories about food allergy of the year.

First documented alpha-gal syndrome fatality from mammalian meat reported

Thomas A.E. Platts-Mills

Researchers have documented the first fatality due to alpha-gal syndrome after consumption of mammalian meat, according to data published in The Journal of Allergy and Clinical Immunology: In Practice. Thomas A.E. Platts-Mills, MD, PhD, professor of medicine in asthma, allergy and immunology at the University of Virginia School of Medicine, discussed the findings. Plus, Douglas H. Jones, MD, FAAAI, FACAAI, cofounder and CEO of the Food Allergy Support Team and member of Healio’s Allergy/Asthma Peer Perspective Board, and Sharon Forsyth, executive director of the Alpha-gal Alliance Action Fund, share their thoughts on the news. Read more.

Use of raw then roasted peanuts reverses allergy for two infants

Two toddlers who had peanut allergy during infancy are now able to safely consume peanuts following a new protocol, according to a presentation at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting. Rachel Kado, MD, allergist and immunologist with the Kado Clinic in Bloomfield Hills, Michigan, discussed the results and what’s next. Read more.

Children with food allergy face ‘substantial’ psychosocial burden

Children with food allergy face a substantial psychosocial burden regardless of their sociodemographic or clinical characteristics, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice. Melissa L. Engel, PhD, postdoctoral fellow, Center for Food Allergy and Asthma Research (CFAAR), Feinberg School of Medicine, discussed the findings. Read more.

Myths of food sensitivity tests: What you need to know

Douglas H. Jones

In his APEX Award-winning column, Food Allergy: Fact vs. Fiction, Healio Allergy/Asthma Peer Perspective Board Member Douglas H. Jones, MD, breaks down five myths surrounding food sensitivity tests and what the evidence actually says. Read more.

Anaphylaxis drives call to add four food allergens to mandatory labels

Goat’s and sheep’s milk, buckwheat, peas and lentils, and pine nut are allergens that could be added to the European mandatory labeling of foods list based on their presence in cases of severe food anaphylaxis, according to study data published in Clinical & Experimental Allergy. Xavier Van der Brempt, MD, PhD, pulmonologist, allergist and group leader at Clinique Saint-Luc Bouge in Belgium, discussed the impact of the results. Read more.

Early blueberry consumption may aid in resolving allergic symptoms, benefit immune system

Some infants fed blueberry powder every day from age 5 months to 12 months had resolved respiratory symptoms, whereas this was not achieved by any infants fed an isocaloric placebo powder, according to data published in Nutrients. Carina Venter, PhD, RD, professor of pediatrics in the section of allergy/immunology at the University of Colorado Anschutz Medical Campus, discussed the trial’s findings. Plus, Lena Bakovic, MS, RDN, CNSC, registered dietitian nutritionist specializing in gut health, heart disease, diabetes, weight management, intuitive eating and general health and wellness at Live it Up, shares her Perspective on this study. Read more.

Peanut patch safe, effective in toddlers 3 years after placebo use

Toddlers with a peanut allergy built tolerance with 3 years of epicutaneous immunotherapy after a year of placebo use, according to a presentation at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting. Read more.

Sequencing identifies specific milk protein causing eosinophilic esophagitis

Gene sequencing enabled researchers to identify the specific milk protein that triggered a patient’s eosinophilic esophagitis, according to a study published in The Journal of Allergy and Clinical Immunology. David A. Hill, MD, PhD, attending physician with the division of allergy and immunology at Children’s Hospital of Philadelphia, discussed the results. Read more.

Families ‘thrilled’ with omalizumab in the year since its approval for food allergy

Robert A. Wood

As we approached the first anniversary of omalizumab’s approval for food allergy, Robert A. Wood, MD, FAAAAI, professor of pediatrics, Johns Hopkins University School of Medicine, told Healio that its use is “definitely going to grow.” Zachary E. Rubin, MD, pediatric allergist at Oak Brook Allergists, also shares his Perspective. Read more.

Peanut consumption safe 3 years after end of oral immunotherapy treatment

Most children who achieved remission with peanut oral immunotherapy continued to eat peanuts freely 3 years after treatment, according to a long-term study of a phase 2b trial population. Mimi Tang, PhD, scientific founder of Prota Therapeutics and director of the Allergy Translation Centre and head of allergy immunology at Murdoch Children’s Research Institute, discussed PRT120 (Prota Therapeutics) and study findings. Read more.