Although component malrotation in total knee arthroplasty may result in a decreased level of improvement from pain, published results showed it did not significantly affect function or quality of life at midterm follow-up.

To determine the effect of femoral, tibial and combined component rotation in primary TKA, researchers measured function with the Knee Society Score, pain and quality of life with the SF-12 score and prosthesis failure. Researchers defined malrotation as being internally rotated from neutral, the femoral component externally rotated greater than 5° and the tibial component internally rotated greater than 6° or the two components combined internally rotated from neutral.