SAN DIEGO — Taking a ‘holiday’ from many osteoporosis drugs can frequently negate gains in bone density, according to a presentation at the 2019 Congress of Clinical Rheumatology West.

Nelson B. Watts, MD, director of osteoporosis and bone health services at Mercy Health in Cincinnati, Ohio, provided some general guidelines for selecting agents for particular patients with osteoporosis. Route of administration — oral or parenteral — should be considered, as should frequency of administration. Some patients may be comfortable with a daily or weekly routine, while others may prefer monthly, quarterly or biannual injections. “Tolerability depends on the agent and the patient,” he noted.