Officials from the Nebraska Department of Health and Human Services have issued a public health advisory following multiple reports of serious adverse events in patients who were treated with unapproved stem cell products, particularly those marketed as containing exosomes.

“This isn’t unique to Nebraska,” Maureen R. Tierney, MD, MSc, health care-associated infections coordinator in the Nebraska Department of Health and Human Services, said in a press release. “People in several other states have also experienced illness after receiving these types of unapproved products. We continue to carefully and actively assess this situation along with our federal partners.”