Centinel Spine LLC announced it received investigational device approval from the FDA to begin a two-level clinical trial for its prodisc C anterior cervical total disc devices: prodisc C Vivo and prodisc C SK.

According to a company press release, the prospective, randomized, multicentered clinical study will compare the prodisc devices with an FDA-approved total disc replacement (TDR) device to validate effectiveness and safety. Centinel Spine will begin the clinical trial immediately at multiple centers in the United States. The interface variations between the prodisc C Vivo and prodisc SK will reportedly allow for surgeons to better match the patient’s anatomy to the implant.