Infectious Disease

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EASL responds to unfavorable DAA review

June 28, 2017

The European Association for the Study of the Liver responded with serious concern to a systematic review published by the Cochrane Group Review that stated, direct acting antivirals “do not seem to have any effects on risk of serious adverse events [but] we could neither confirm nor reject that DAAs had any clinical effects.”

“The review examines the intervention in a clinical vacuum that fails to accept that DAA treatment to attain [a sustained virologic response] is a pivotal outcome of treatment, and does not accept the likelihood that an SVR will reduce the risks of long-term outcomes of hepatitis C,” EASL governing board members and board directors wrote in a recent editorial published online in Journal of Hepatology. “With this deduction comes responsibility. The uncertainty created by the ill-conceived Cochrane group’s conclusions and the attendant press publicity could grievously affect policy making, and constrain the gathering momentum for diagnosis, testing and linkage to care of individuals with hepatitis C. It will create dangerous confusion in the mind of patients treated or about to be treated and their families.”

In the Journals

CDC annual report: Prescription drug use, obesity rates increase

June 28, 2017
Life expectancy is up and tobacco use is down, but there are still several concerning health indicators in the CDC’s 40th annual report on long-term trends in…
In the Journals Plus

Low-cost, yeast-based assay reliably detects fungal pathogens

June 28, 2017
Researchers at Columbia University have developed a tool that uses baker’s yeast to detect fungal pathogens responsible for human disease, agricultural damage…

ACP: Supreme Court permitting parts of travel ban ‘creates uncertainty’

June 28, 2017
The June 26 Supreme Court decision to allow parts of President Trump’s travel ban on six Muslim-majority countries to take effect generates uncertainty and…

Kenya introduces generic version of first-line HIV drug

June 28, 2017
The Kenyan government is partnering with Unitaid to provide dolutegravir, a first-line drug, to people living with HIV, according to a press release. The effort makes…
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CME

HPV Immunization: Ensuring Your Patients Do Not Slip through the Cracks

This activity is supported by an educational grant from Merck & Co., Inc.

Vaccination rates for the human papillomavirus (HPV) continue to be below those of other vaccines recommended for…
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In the Journals Plus

Lethal DMAC persists among patients with HIV

June 27, 2017
Despite the availability of effective ART, disseminated Mycobacterium avium complex, or DMAC, is still a mortal danger…
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VIDEO: Vaccine significantly reduces risk for influenza-related death in children

June 5, 2017
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