Women who received metronidazole with the CDC-recommended antibiotic regimen of ceftriaxone and doxycycline for pelvic inflammatory disease, or PID, experienced better clinical and microbiologic outcomes than women who received only ceftriaxone and doxycycline, according to a study published in Clinical Infectious Diseases.
“Current CDC guidelines recommend a single intramuscular dose of ceftriaxone and 14 days of doxycycline, with or without the addition of metronidazole for 14 days,” Harold C. Wiesenfeld, MD, CM, professor of obstetrics, gynecology and reproductive sciences at the University of Pittsburgh, told Healio. “The results of this clinical trial support routinely adding metronidazole to the ceftriaxone and doxycycline regimen for the treatment of women with acute pelvic inflammatory disease.”
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