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FDA advisory committee split on opinion of adjuvant Sutent for renal cell carcinoma

September 19, 2017

The FDA’s Oncologic Drug Advisory Committee today voted 6-6 on whether the risk-benefit profile of sunitinib malate is acceptable for the adjuvant treatment of patients with a high-risk for recurrent renal cell carcinoma following nephrectomy.

The committee considered data from the S-TRAC trial, which randomly assigned patients at high risk for recurrent renal cell carcinoma following nephrectomy to 1 year of sunitinib (Sutent, Pfizer Oncology; n = 309) or placebo (n = 306). Patients assigned sunitinib received 50-mg doses for 4 weeks following by 2 weeks off, and the dose could be reduced to 37.5 mg.

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VIDEO: Additional treatment with ALK inhibitor after progression shows promise in non-small cell lung cancer

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CME

Diagnostic and Therapeutic Challenges in Von Willebrand Disease

This activity is supported by an educational grant from Shire.

With the significant variability in the subtypes and clinical manifestations of von Willebrand disease (VWD), diagnosis…
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VIDEO: LATITUDE, STAMPEDE trials provide ‘practice-changing’ findings in prostate cancer

July 15, 2017
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Resource Centers
European Society for Medical Oncology Congress

European Society for Medical Oncology Congress

CME

Multiple Myeloma Patient Management: Embracing New Advancements, Overcoming New Challenges

Support for this activity has been provided through educational grants from Amgen; Celgene Corporation; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Oncology.

The multiple myeloma clinical landscape has evolved significantly, with not only 10 new drugs but also new staging…
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