Reduced circulating eosinophils and chronic bronchial infection raise the risk for pneumonia in patients with COPD treated with inhaled corticosteroids, researchers reported in the American Journal of Respiratory and Critical Care Medicine.
Results from the post hoc long-term observational study of a historical cohort of 201 patients with moderate to severe COPD, as defined by Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations, showed that risk for pneumonia was about 63% higher in patients with chronic bronchial infection and about 97% higher in those with circulating blood eosinophil levels of less than 100 cells/µL. Additionally, the risk for pneumonia was nearly threefold higher among patients treated with inhaled corticosteroids who also had chronic bronchial infection and reduced circulating eosinophils.
CHEST Annual Meeting
Search Healio's robust listing of national and international medical meetings.
Tell us what you think about Healio.com »
Get the latest news and education delivered to your inbox
©2020 Healio All Rights Reserved.