June 30, 2017
Results from this recently published study indicated the N-acetylaspartate to creatine ratio and the volume of activation in the primary motor cortex can be used to differentiate between mild and moderate cervical spondylotic myelopathy.
Researchers identified 28 patients with cervical spondylotic myelopathy who underwent 3-T MRI scans before surgery and at 6 months postoperatively. The modified Japanese Orthopaedic Association questionnaire was used to determine severity of disease. Investigators also performed two MRI scans 6 months apart in 10 healthy control patients. In the patient cohort, investigators measured the metabolite levels from the primary motor cortex (M1) contralateral to the greater deficit side. In the controls, they measured both sides. A right finger-tapping paradigm was used to assess motor function.