TBI characterization and classification need change for improved treatment

Researchers have announced a study to analyze 5,400 patients presenting within 24 hours of a clinical traumatic brain injury diagnosis in an attempt to personalize treatment and improve outcomes.

Investigators will conduct a multicenter, longitudinal, prospective, observational study to improve characterization and classification of traumatic brain injury (TBI) and to identify best clinical care.

“Advanced neuroimaging and genomic and biomarker data will be used to improve characterization, and analyses will include neuroinformatics approaches to address variations in process and clinical care. Results will be integrated with living systematic reviews in a process of knowledge transfer,” Andrew I. R. Maas, MD, PhD, and colleagues wrote in the study abstract.

The CENTER-TBI study is designed to identify more effective and efficient treatment provision, thus improving outcomes and reducing costs, according to the researchers. In addition, the study will hopefully deliver early scientific advances that could improve the care of patients with TBI, and provide a rich investment for future biomedical research, Maas and colleagues wrote. – by Robert Linnehan

Reference: Mass AIR, et al. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study. J Spine Neurosurg. 2015;doi:10.1227/NEU.0000000000000575..

Researchers have announced a study to analyze 5,400 patients presenting within 24 hours of a clinical traumatic brain injury diagnosis in an attempt to personalize treatment and improve outcomes.

Investigators will conduct a multicenter, longitudinal, prospective, observational study to improve characterization and classification of traumatic brain injury (TBI) and to identify best clinical care.

“Advanced neuroimaging and genomic and biomarker data will be used to improve characterization, and analyses will include neuroinformatics approaches to address variations in process and clinical care. Results will be integrated with living systematic reviews in a process of knowledge transfer,” Andrew I. R. Maas, MD, PhD, and colleagues wrote in the study abstract.

The CENTER-TBI study is designed to identify more effective and efficient treatment provision, thus improving outcomes and reducing costs, according to the researchers. In addition, the study will hopefully deliver early scientific advances that could improve the care of patients with TBI, and provide a rich investment for future biomedical research, Maas and colleagues wrote. – by Robert Linnehan

Reference: Mass AIR, et al. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study. J Spine Neurosurg. 2015;doi:10.1227/NEU.0000000000000575..