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Elevated adipsin linked with pulmonary arterial hypertension in patients with systemic sclerosis

June 30, 2017

Among patients with systemic sclerosis, elevated levels of adipsin were linked with pulmonary arterial hypertension, according to a recently published analysis.

“Taken together, these findings suggest a previously unrecognized pathogenic role for adipsin in [systemic sclerosis] SSc and SSc [pulmonary arterial hypertension] PAH, and highlight adipsin as a novel marker of vascular manifestations with important prognostic and potentially therapeutic value,” Benjamin D. Korman, MD, from Northwestern University, and colleagues wrote. “Moreover, in light of the essential role of adipsin in modulating complement pathway activity, our results implicate the complement system in SSc-associated PAH.”

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Epitope-based blood test may identify active systemic sclerosis

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MADRID — A conformational epitope-based assay may be effective in identifying systemic sclerosis patients whose disease is active, regardless of whether their…

Unspoken and Undiagnosed: Addressing Sex and Intimacy Issues in Rheumatic Disease

Healio Rheumatology, June 2017
Sexual dysfunction and intimacy issues may rank high among the complaints reported by patients with rheumatic diseases, but these complaints often remain unaddressed in…
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Nailfold videocapillaroscopy may aid in early diagnosis of systemic sclerosis

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MADRID —  Nailfold videocapillaroscopy demonstrated feasibility as a diagnostic tool for systemic sclerosis, particularly among patients with Raynaud’s…
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Ace the Case: A 29-year-old Woman with Psoriasis Vulgaris

There is no commercial support for this activity.

This “Ace the Case” study will discuss the assessment and treatment of a 29-year-old woman with Psoriasis Vulgaris…
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Rheumatology Nurses Society Annual Conference

Rheumatology Nurses Society Annual Conference


The Role of the Inflammatory Cascade in the Pathogenesis and Treatment of Psoriatic Arthritis: New and Emerging Therapies

This activity is supported by educational grants from Celgene Corporation and Novartis Pharmaceuticals Corporation.

The workings of the inflammatory cascade are not fully defined, but recent findings have demonstrated roles for novel…
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