Scleroderma

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Elevated adipsin linked with pulmonary arterial hypertension in patients with systemic sclerosis

June 30, 2017

Among patients with systemic sclerosis, elevated levels of adipsin were linked with pulmonary arterial hypertension, according to a recently published analysis.

“Taken together, these findings suggest a previously unrecognized pathogenic role for adipsin in [systemic sclerosis] SSc and SSc [pulmonary arterial hypertension] PAH, and highlight adipsin as a novel marker of vascular manifestations with important prognostic and potentially therapeutic value,” Benjamin D. Korman, MD, from Northwestern University, and colleagues wrote. “Moreover, in light of the essential role of adipsin in modulating complement pathway activity, our results implicate the complement system in SSc-associated PAH.”

Meeting News

Epitope-based blood test may identify active systemic sclerosis

June 16, 2017
MADRID — A conformational epitope-based assay may be effective in identifying systemic sclerosis patients whose disease is active, regardless of whether their…
Feature

Unspoken and Undiagnosed: Addressing Sex and Intimacy Issues in Rheumatic Disease

Healio Rheumatology, June 2017
Sexual dysfunction and intimacy issues may rank high among the complaints reported by patients with rheumatic diseases, but these complaints often remain unaddressed in…
Meeting News

Nailfold videocapillaroscopy may aid in early diagnosis of systemic sclerosis

June 14, 2017
MADRID —  Nailfold videocapillaroscopy demonstrated feasibility as a diagnostic tool for systemic sclerosis, particularly among patients with Raynaud’s…
CME

Giant Cell Arteritis: New Findings on Diagnostic Strategies and Emerging Therapies

This activity is supported by an educational grant from Genentech, Inc.

Giant cell arteritis is a potentially debilitating rheumatologic disease that afflicts predominantly older men and…
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Video
Meeting News Coverage

VIDEO: Khanna discusses safety, efficacy of tocilizumab for systemic sclerosis

June 11, 2016
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Biosimilars in the US

Biosimilars in the US

CME

The Patient with Back Pain

No commercial support for this activity.

Back pain is a common disorder, with nearly 80% of adults experiencing lower back pain over the course of their…
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