Psoriatic Arthritis

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PsA scoring systems showed moderate sensitivity, high specificity in detecting change

November 3, 2017

The quantifying of radiographic axial psoriatic arthritis through currently available scoring systems has moderate sensitivity but high specificity for identifying true change, according to results.

Researchers obtained radiographs of 105 patients with axial PsA from the University of Toronto PsA clinic. Patients had serial radiographs, separated by at least 2 years, and obtained since 2003. Researchers extracted two sets of axial radiographs. Three radiologists blinded to name and order of examination scored the radiographs using the scoring model of axial radiograph Toronto (SMART) application. Using the application, they automatically calculated Bath ankylosing spondylitis radiology index for the spine (BASRI-s), the modified stroke ankylosing spondylitis spine score (mSASSS), the radiographic ankylosing spondylitis spine score (RASSS) and PsA spondylitis radiology index (PASRI) scores. The existence of true radiographic progression was determined by an independent expert who viewed the radiographs with knowledge of the chronology. Researchers identified true change by determining the sensitivity, specific and odds ratios for every 1-unit increase in scores.

In the Journals

Psoriasis, inflammatory diseases increase risk for cirrhosis, fatty liver

November 2, 2017
Patients with inflammatory disorders, especially psoriasis and psoriatic arthritis, had an elevated risk for severe liver disease such as nonalcoholic fatty liver…

Janssen Biotech receives FDA approval for Simponi Aria for the treatment of active PsA, AS

October 23, 2017
Janssen announced it has received FDA approvals for Simponi Aria for the treatment of adults with psoriatic arthritis or active ankylosing spondylitis, according to a…
Education Lab

Ace the Case: A 29-year-old Woman With Psoriasis Vulgaris

Healio Rheumatology, October 2017
A 29-year-old woman presents to the clinic to establish care for her psoriasis vulgaris. She states her psoriasis began when she was 22 years old and she has been…
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CME ABIM MOC

Ace the Case: A 29-year-old Woman with Psoriasis Vulgaris

There is no commercial support for this activity.

This “Ace the Case” study will discuss the assessment and treatment of a 29-year-old woman with Psoriasis Vulgaris…
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American College of Rheumatology Annual Meeting

American College of Rheumatology Annual Meeting

CME

The Role of the Inflammatory Cascade in the Pathogenesis and Treatment of Psoriatic Arthritis: New and Emerging Therapies

This activity is supported by educational grants from Celgene Corporation and Novartis Pharmaceuticals Corporation.

The workings of the inflammatory cascade are not fully defined, but recent findings have demonstrated roles for novel…
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