Meeting News

Young athletes with previous knee injury had higher risk of OA

LAS VEGAS — Young athletes who previously sustained an intra-articular knee injury had a higher risk of structural changes associated with future osteoarthritis, according to results presented at the Osteoarthritis Research Society International World Congress.

“Young adults around the age of 22 [years] who sustained an intra-articular knee injury when they were about 16 [years of age] playing sport appeared to be at a higher risk of structural changes associated with future osteoarthritis,” Jackie L. Whittaker, PhD, said in her presentation.

Jackie Whittaker
Jackie L. Whittaker

Whittaker and colleagues compared 100 patients who had an intra-articular knee injury while participating in sports with 100 control patients matched for age, sex and sport. Primary outcome measure was a structural outcome of MRI-defined osteoarthritis (OA), while secondary outcomes included KOOS measures, weekly physical activity and normalized knee extensor isometric torque, according to Whittaker.

Results showed patients who had a previous injury had a 25% higher prevalence of MRI-defined OA 3 years to 10 years after injury. Whittaker noted patients who had a torn ACL or injured meniscus appeared to have the highest risk of structural changes. She said patients who had a previous injury scored lower on the KOOS score, with the most significant differences in the symptom subscale and the knee-related quality of life.

“Although we did not see a difference between the two groups with respect to the total metabolic equivalence of physical activity across the week, we did see that those with a previous injury had lower aerobic fitness, estimated with a 20-meter shuttle run,” Whittaker said.

She added patients with previous injury were two-times more likely to be in the lowest quartile for physical activity. Results showed weaker knee extensors and weaker knee flexors among patients who had a previous injury.

“Previously injured participants had a higher BMI, a higher fat mass index and they had higher abdominal fat,” Whittaker said. “When we dichotomized what we saw was those with a previous injury were about 2.5-times more likely to be overweight or obese by BMI; 4.4-times more likely to be in the upper quartile for fat mass index; and almost six-times more likely to be in the upper quartile for abdominal fat.” – by Casey Tingle

Reference:

Whittaker JL, et al. Paper #65. Presented at: Osteoarthritis Research Society International World Congress; April 27-30, 2017; Las Vegas.

Disclosure: Whittaker reports relevant financial disclosures.

LAS VEGAS — Young athletes who previously sustained an intra-articular knee injury had a higher risk of structural changes associated with future osteoarthritis, according to results presented at the Osteoarthritis Research Society International World Congress.

“Young adults around the age of 22 [years] who sustained an intra-articular knee injury when they were about 16 [years of age] playing sport appeared to be at a higher risk of structural changes associated with future osteoarthritis,” Jackie L. Whittaker, PhD, said in her presentation.

Jackie Whittaker
Jackie L. Whittaker

Whittaker and colleagues compared 100 patients who had an intra-articular knee injury while participating in sports with 100 control patients matched for age, sex and sport. Primary outcome measure was a structural outcome of MRI-defined osteoarthritis (OA), while secondary outcomes included KOOS measures, weekly physical activity and normalized knee extensor isometric torque, according to Whittaker.

Results showed patients who had a previous injury had a 25% higher prevalence of MRI-defined OA 3 years to 10 years after injury. Whittaker noted patients who had a torn ACL or injured meniscus appeared to have the highest risk of structural changes. She said patients who had a previous injury scored lower on the KOOS score, with the most significant differences in the symptom subscale and the knee-related quality of life.

“Although we did not see a difference between the two groups with respect to the total metabolic equivalence of physical activity across the week, we did see that those with a previous injury had lower aerobic fitness, estimated with a 20-meter shuttle run,” Whittaker said.

She added patients with previous injury were two-times more likely to be in the lowest quartile for physical activity. Results showed weaker knee extensors and weaker knee flexors among patients who had a previous injury.

“Previously injured participants had a higher BMI, a higher fat mass index and they had higher abdominal fat,” Whittaker said. “When we dichotomized what we saw was those with a previous injury were about 2.5-times more likely to be overweight or obese by BMI; 4.4-times more likely to be in the upper quartile for fat mass index; and almost six-times more likely to be in the upper quartile for abdominal fat.” – by Casey Tingle

Reference:

Whittaker JL, et al. Paper #65. Presented at: Osteoarthritis Research Society International World Congress; April 27-30, 2017; Las Vegas.

Disclosure: Whittaker reports relevant financial disclosures.

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