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Diagnosis and Treatment of Pemphigus Vulgaris: Strategies for Optimal Multidisciplinary Care

Healio Rheumatology, November 2017

A 37-year-old woman presents with oral lesions consistent with pemphigus vulgaris and is treated with prednisone 1 mg/kg daily in combination with methotrexate 15 mg/week. Although she initially responds to treatment, any attempt to decrease or taper dose is met with disease flare. After 13 months on treatment, her symptoms return, with new oral lesions and blistering on the upper back. She is initially switched from prednisone to betamethasone, but has no response and develops a mild case of oral candidiasis. Her oral lesions increase in severity, resulting in difficulty eating and brushing teeth.

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American College of Rheumatology Annual Meeting

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This activity is supported by educational grants from AbbVie, Inc.; Lilly USA, LLC; and Sanofi Genzyme and Regeneron Pharmaceuticals.

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