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Patients treated with febuxostat for early gout had lower overall rate of flares

Patients treated with febuxostat for early gout had lower overall rate of flares
October 4, 2017

Results from this study demonstrated patients with early gout treated with febuxostat had improvements in MRI synovitis and a decrease in gout flares compared with patients in a placebo group.

“Typically, studies of urate-lowering therapy recruit people with longstanding gout,” Nicola Dalbeth, MD, FRACP, study co-author, rheumatologist and professor at the department of medicine at the University of Auckland in New Zealand, told Healio Rheumatology.  “This placebo-controlled [randomized controlled trial] RCT examined the effect of urate-lowering therapy in people with earlier disease who had experienced only one or two gout flares. The key finding of this study was that in this patient group, the urate-lowering drug febuxostat reduced joint inflammation detected by MRI scanning and also reduced the frequency of gout flares over the 2-year study period.”

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