Please refer to the full Prescribing Information at CIMZIAhcp.com.
In an analysis of several studies, 10% to 40% of patients with nr-axSpA may convert to ankylosing spondylitis (AS) over a period of 2 to 10 years. However, almost 60% of patients with nr-axSpA do not progress to AS over this time frame.1 Objective signs of inflammation, such as elevated C-reactive protein (CRP) and active sacroiliitis on magnetic resonance imaging (MRI), are some of the strongest predictors of conversion to AS.2
1. Protopopov M, Poddubnyy D. Radiographic progression in non-radiographic axial spondyloarthritis. Expert Rev Clin Immunol. 2018;14(6):525-533.
2. Baraliakos X, Braun J. Non-radiographic axial spondyloarthritis and ankylosing spondylitis: what are the similarities and differences? RMD Open. 2015;1(suppl 1):e000053. doi: 10.1136/rmdopen-2015-000053.
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Version: August 2019
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