The CDC has expanded its recommendation of a short-course combination regimen of once-weekly isoniazid and rifapentine for the treatment of latent tuberculosis infection to include children aged 2 to 11 years and patients with HIV/AIDS taking antiretroviral medications.
Children with latent tuberculosis infection (LTBI) should be treated to prevent them from developing active TB disease, according to health officials. However, the CDC’s recommendations from 2011 limited the use of the shortest regimen currently available — once-weekly isoniazid and rifapentine for 12 weeks (3HP), Andrey S. Borisov, MD, medical epidemiologist at the CDC’s Division of Tuberculosis Elimination, told Infectious Diseases in Children.
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