CHICAGO — First-line pembrolizumab conferred longer median OS than chemotherapy among patients with non-small cell lung cancer and PD-L1 expression, according to results of the phase 3 KEYNOTE-042 clinical trial presented during the plenary session at ASCO Annual Meeting.

Patients with a PD-L1 expression of 1% or greater first treated with pembrolizumab (Keytruda, Merck) lived a median of 4 to 8 months longer than patients who received chemotherapy.