Risk-targeted low-dose CT testing is the most effective approach to reduce lung cancer mortality; however, gains in benefits, such as life-years saved, quality-adjusted life-years and cost-effectiveness, are not substantial, according to two studies published in Annals of Internal Medicine.
“The U.S. Preventive Services Task Force recommends annual low-dose CT lung cancer screening for persons aged 55 to 80 years who currently smoke or quit within the past 15 years and have at least a 30–pack-year history of cigarette smoking. ... These criteria may exclude smokers at high risk for lung cancer who would have been selected for CT screening by individual risk calculators that more specifically account for demographic, clinical and smoking characteristics,” Li C. Cheung, PhD, from the National Cancer Institute, and colleagues wrote.
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