Clofazimine was a safe and well-tolerated part of a multidrug regimen used to treat children with odontogenic Mycobacterium abscessus infection that was caused during an outbreak at a dental facility, according to study results published in the Journal of the Pediatric Infectious Diseases Society.
“M. abscessus is a very difficult infection to treat due to many factors, including antimicrobial resistance and adverse effects from the treatment medications,” Felice C. Adler-Shohet, MD, FAAP, director of outpatient services for the department of infectious diseases at the Children’s Hospital of Orange County, California, told Infectious Diseases in Children. “In addition, this infection seems to be increasing in incidence. Our results show that clofazimine offers one more possible antimicrobial agent as part of our armamentarium to help fight this infection in children.”
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