Critically ill children who experience severe hyperoxemia in the pediatric ICU may have a higher risk for in-hospital mortality, according to data published in JAMA Network Open.
In the retrospective cohort study conducted over 10 years in a pediatric ICU, the researchers found an independent association between severe hyperoxemia, defined as a partial pressure of oxygen (PaO2) in the arterial blood of at least 300 mm Hg, and in-hospital mortality (adjusted OR = 1.78; 95% CI, 1.36-2.33).
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