Substance Use Disorders

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Preliminary findings show safety of intranasal OPNT002 for alcohol addiction

July 25, 2017

Opiant Pharmaceuticals Inc. recently announced phase 1 data showing efficacy and safety of OPNT002, intended for treatment of alcohol use disorder, among healthy individuals.

“We are very excited by the observed changes in the pharmacokinetic properties of intranasal naltrexone when combined with Intravail, particularly the ability of Intravail to reduce the time needed to reach maximum plasma concentrations, which implies a more rapid onset of action,” Phil Skolnick, PhD, DSc, chief scientific officer at Opiant Pharmaceuticals Inc., said in a press release. “Although additional clinical work is required, the ability to rapidly deliver an intranasal dose of naltrexone on an ‘as needed’ basis has the potential to offer patients a much-needed innovation in the treatment of [alcohol use disorder].”

CDC awards $12 million toward opioid epidemic

July 18, 2017
The CDC recently awarded more than $12 million in funding for the opioid epidemic to 23 states and Washington, D.C. “The opioid epidemic is a scourge on our nation…
In the Journals

Opioid dose reduction may benefit patients with chronic pain

July 17, 2017
Reducing or discontinuing long-term opioid therapy may improve pain, function and quality of life among patients with chronic pain; however, these findings are supported…
In the Journals

Tramadol comparable to buprenorphine for opioid withdrawal

July 14, 2017
Extended-release tramadol was more effective than clonidine for opioid withdrawal symptoms and was comparable to buprenorphine, according to recent findings. …
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CME

Prescription Opioids and Addiction

Psychiatric Annals, October 2015, Volume 45 Issue 10
Why are opioid medications prescribed in large quantities and high frequency when there is little or no proven efficacy…
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CNE

Journal of Psychosocial Nursing and Mental Health Services July 2014 CNE Activity

This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated.

Topics include parents’ experiences with child’s admission to acute care, diet restrictions and atypical antipsychotic…
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VIDEO: Evidence-based treatments for comorbid ADHD, cannabis use disorder

May 31, 2017
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