Substance Use Disorders

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Monthly buprenorphine depot RBP-6000 effective, safe for opioid addiction

June 23, 2017

Indivior recently presented phase 3 findings that indicated efficacy and safety of RBP-6000, an investigational once-monthly injectable buprenorphine in the Atrigel delivery system, for treatment of moderate-to-severe opioid use disorder.

“The clinical data from our phase 3 study also showed that outcomes with RBP-6000 are consistent across other secondary clinical endpoints, including control of craving and withdrawal symptoms, as compared to placebo,” Christian Heidbreder, PhD, chief scientific officer of Indivior, said in a press release. “These outcomes started with the first dose of RBP-6000, which achieved buprenorphine plasma concentrations 2 ng/mL and predicted whole brain µ-opioid receptor occupancy of 70%, and were also maintained for the 1-month dosing intervals and for the entire treatment duration.”

Meeting News

Patient engagement is critical to treat chronic pain, opioid use disorder

June 22, 2017
PHILADELPHIA —  Successfully treating patients with chronic pain and opioid use disorder must involve the patient being actively engaged in self-management of…
In the Journals

Pregnancy has protective effect on drug abuse

June 20, 2017
Risk for drug abuse was substantially lower during pregnancy, suggesting a potential protective effect, according to recent findings. “The causal nature of the…
Meeting News

AMA supports efforts to combat ‘dangerous’ synthetic, injectable drugs

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AMA delegates at the annual meeting underway in Chicago voted to back several efforts to close a gap in the nation’s ability to identify, mitigate and regulate the…
CME

Prescription Opioids and Addiction

Psychiatric Annals, October 2015, Volume 45 Issue 10
Why are opioid medications prescribed in large quantities and high frequency when there is little or no proven efficacy…
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Journal of Psychosocial Nursing and Mental Health Services Jan 2015 CNE Activity

This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated.

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American Psychiatric Association Annual Meeting

American Psychiatric Association Annual Meeting

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Meeting News

Monthly buprenorphine depot RBP-6000 effective, safe for opioid addiction

June 23, 2017
Indivior recently presented phase 3 findings that indicated efficacy and safety of RBP-6000, an investigational once-monthly injectable buprenorphine…

Meeting News

Patient engagement is critical to treat chronic pain, opioid use disorder

June 22, 2017
PHILADELPHIA —  Successfully treating patients with chronic pain and opioid use disorder must involve the patient being actively engaged…

In the Journals

Pregnancy has protective effect on drug abuse

June 20, 2017
Risk for drug abuse was substantially lower during pregnancy, suggesting a potential protective effect, according to recent findings. “The…

Meeting News

AMA supports efforts to combat ‘dangerous’ synthetic, injectable drugs

June 13, 2017
AMA delegates at the annual meeting underway in Chicago voted to back several efforts to close a gap in the nation’s ability to identify…

Treatment rates low for substance use disorders in US

June 12, 2017
Findings in a SAMHSA report indicated approximately 4% of individuals with an alcohol use disorder received specialty treatment for the disorder in…

FDA calls for removal of Opana ER due to abuse risks

June 9, 2017
Due to concerns that risks related to abuse outweigh the benefits of reformulated Opana ER (oxymorphone hydrochloride) the FDA is requesting that…

In the Journals

Experts outline priorities for addressing opioid use in women who are pregnant

June 9, 2017
Leaders of NIH, CDC, the American Congress of Obstetricians and Gynecologists, the AAP, the Society for Maternal-Fetal Medicine and the March of…

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Less benefit from light alcohol consumption than previously thought

June 9, 2017
The apparent observed health benefits of stable moderate drinking, and the risks associated with abstention, may be overstated among middle-aged…

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Current Medical and Legal Status for Smoked “Medical Marijuana” and Addiction

Psychiatric Annals, June 2017, Volume 47 Issue 6
“Medical marijuana” does not meet the legal definition of drug as defined by the Food and Drug Administration (FDA) in the US.1 The drug…

HHS awards $70 million to combat opioid epidemic

June 2, 2017
HHS recently announced more than $70 million in grants to combat the opioid epidemic by preventing opioid overdose deaths and provide treatment for…

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