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Study shows 'alarming' long-term declines in schizophrenia functioning

August 15, 2017

Functioning scores decreased among individuals who received inpatient treatment for psychosis 20 years after discharge, particularly among those with schizophrenia or schizoaffective disorder.

“Emil Kraepelin considered declining course a distinguishing feature of schizophrenia (dementia praecox) in contrast to the nondeclining, episodic course of mood disorders with psychosis. Others have challenged this view, suggesting that a downward trajectory is not typical of schizophrenia and that outcomes tend to improve over time,” Roman Kotov, PhD, of Stony Brook University, New York, and colleagues wrote.

In the Journals

Mortality, self-harm lower with clozapine use in schizophrenia

August 4, 2017
Clozapine use in treatment-resistant schizophrenia was associated with lower all-cause mortality and self-harm rates, according to recent findings. “Clozapine is…
In the Journals

MIN-101 reduces negative symptoms in schizophrenia

August 1, 2017
MIN-101, a 5-HT2a and sigma2 antagonist from Minerva Neurosciences, significantly reduced negative symptoms in schizophrenia and was well-tolerated, according to recent…
In the Journals

Abnormal insulin levels found in first-episode schizophrenia

July 27, 2017
Recent findings indicated impaired insulin/glucose homeostasis in drug-naïve individuals with first-episode schizophrenia. “Before the introduction of…
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Comorbidities in Schizophrenia: Challenges for Researchers and Clinicians

Psychiatric Annals, October 2013, Volume 43 Issue 10
1. Provide strategies for combining psychotropics in treating persons with schizophrenia plus other psychiatric…
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Journal of Psychosocial Nursing and Mental Health Services January 2017 CNE Activity

This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated.

Topics include telephone intervention for medication adherence in outpatients with schizophrenia spectrum disorders…
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