Journal of Psychosocial Nursing and Mental Health Services

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Drugs to Treat Various Pain Conditions

Abstract

Table

A handy source of up-to-date information on current medications for psychiatric illnesses…

Table

A handy source of up-to-date information on current medications for psychiatric illnesses

Generic (Brand) NameFDA–Approved Pain-Related IndicationsNon-FDA–Approved Pain-Related IndicationsHabit Forming?Prescription or OTC
NARCOTIC (OPIOID) DRUGS
Acetominophen/benzhydrocodone (Apadaz®), acetominophen/oxycodone (Xartemis XR®), buprenorphine (Buprenex®, Belbuca®), buprenorphine transdermal (Butrans®), codeine (Tylenol 3® and others), fentanyl (Fentora®, Onsolis, and others), hydrocodone (Hysingla®ER, Vantrela ER®, Vicodin®, Zohydro®, and others), hydromorphone (Exalgo®, Palladone®), meperidine (Demerol®), methadone (Methadose® and others), morphine (Arymo ER®, Avinza®, Morphabond®, and others), morphine sulfate/naltrexone HCl (Embeda®), naloxone/oxycodone (Targiniq ER®), pentazocine HCl/naloxone HCl (Talwin® Nx), oxycodone (Percocet®, RoxyBond®, Xtampa® ER, and others), oxycodone/naltrexone (Troxyca® ER), oxymorphone (Numorphan®), and othersPainHeadache, migraine, fibromyalgia, neuropathic painYesPrescription
Fentanyl citrate (Lazanda® nasal spray), fentanyl sublingual spray (Subsys®)Breakthrough cancer pain
Fentanyl sublingual tablets (Abstral®)Breakthrough cancer pain in opioid-tolerant patients
NON-NARCOTIC DRUGS
Acetaminophen (Tylenol®)Pain, headache, dysmenorrheaMigraine, fibromyalgia, neuropathic painNoOTC
AspirinPain, headache, migraine, anti-inflammatoryDysmenorrhea, fibromyalgia, neuropathic painNoOTC
Diflunisal (Dolobid®)Pain, anti-inflammatoryDysmenorrhea, headache, migraine, fibromyalgia, neuropathic painNoPrescription
NONSTEROIDAL ANTI-INFLAMMATORY (NSAID) DRUGS
Diclofenac (Cambia™, Cataflam®, Dyloject®, Zipsor, Zorvolex®), etodolac (Lodine®, Lodine XL®), ibuprofen (Advil®, Motrin®, and others), indomethacin (Tivorbex®), ketoprofen (Orudis®, Oruvail®), ketorolac (Sprix®, Toradol®), naproxen (Aleve®, Aleve PM®, Naprosyn®), piroxicam (Feldene®), sulindac (Clinoril®), and othersPain, headache, migraine, dysmenorrhea, anti-inflammatoryFibromyalgia, neuropathic painNoOTC and prescription (depending on medication strength)
Meloxicam (Vivlodex®)Osteoarthritis painPrescription
COX-2 INHIBITOR NSAID DRUG
Celecoxib (Celebrex®)Pain, dysmenorrhea, anti-inflammatoryHeadache, migraine, fibromyalgia, neuropathic painNoPrescription
ERGOT ALKALOID DRUGS
Dihydroergotamine mesylate (Migranal®)Migraine, cluster headachesNoneNoPrescription
Ergotamine tartrate (Ergomar®)Migraine, vascular headachesNoneNoPrescription
Methysergide maleate (previously available in the United States as Sansert®)Vascular headachesNoneNoPrescription
SEROTONIN RECEPTOR ANTAGONIST DRUGS
Almotriptan malate (Axert®), eletriptan HBr (Relpax®), frovatriptan succinate (Frova®), naratriptan HCl (Amerge®), rizatriptan benzoate (Maxalt®), sumatriptan iontophoretic transdermal system (Zecuity®), sumatriptan nasal powder (Onzetra™ Xsail™), sumatriptan succinate (Alsuma®, Imitrex®), zolmitriptan (Zomig®)MigraineCluster headachesNoPrescription
ANTIDEPRESSANT DRUGS
Tricyclic antidepressants: amitriptyline (Elavil®), desipramine (Norpramine®), imipramine (Tofranil®), nortriptyline (Aventyl®, Pamelor®), and othersNoneaPain, headache, migraine, fibromyalgia, neuropathic painNoPrescription
Bupropion (Forfivo XL®, Wellbutrin®, Wellbutrin SR®, Wellbutrin XL®)NoneaPain, neuropathic painNoPrescription
Duloxetine (Cymbalta®)Diabetic peripheral neuropathy, fibromyalgia, chronic musculoskeletal painNoneNoPrescription
Milnacipran (Savella®), Levomilnacipran (Fetzima®)Fibromyalgia NonePain PainNo NoPrescription Prescription
Venlafaxine (Effexor®, Effexor XR®) Desvenlafaxine (Pristiq®)NoneaNonePain, headache, migraine, fibromyalgia, neuropathic pain PainNo NoPrescription Prescription
ANTICONVULSANT DRUGS
Carbamazepine (Carbatrol®, Equetro®, Tegretol®, Tegretol XR®)Trigeminal neuralgiaPain, neurogenic painNoPrescription
Divalproex sodium (Depakote®, Depakote ER®), valproic acid (Depakene®, Stavzor®)MigraineHeadache, neuropathic painNoPrescription
Eslicarbazepine (Aptiom®)NoneNeuropathic painNoPrescription
Gabapentin (Gralise®b , Neurontin®)Post-herpetic neuralgiaPain, neuropathic pain, migraine, fibromyalgia, prevention of postoperative painNoPrescription
Lacosamide (Vimpat®)NoneaDiabetic peripheral neuropathyNoPrescription
Lamotrigine (Lamictal®)NoneaMigraine, trigeminal neuralgiaNoPrescription
Levetiracetam (Keppra®)NoneaMigraineNoPrescription
Oxcarbazepine (Trileptal®)NoneNeuropathic painNoPrescription
Phenytoin (Dilantin®)NoneaChronic painNoPrescription
Pregabalin (Lyrica®)Diabetic peripheral neuropathy, post-herpetic neuralgia, fibromyalgiaCentral painNoPrescription
Topiramate (Topamax®)MigraineHeadache, neuropathic painNoPrescription
MONOCLONAL ANTIBODIES
Erenumab-aooe (Aimovig®)MigraineNoPrescription
Fremanezumab-vfrm (Ajovy®)MigraineNoPrescription
Galcanezumab-gnlm (Emgality®)MigraineNoPrescription
MISCELLANEOUS DRUGS
Capsaicin (Capsagel®, Qutenza®, Zostrix®)Pain, anti-inflammatoryNeuropathic painNoOTC
Lithium (Eskalith®)NoneCluster headachesNoPrescription
Metoprolol (Toprol®, Lopressor®)NoneMigraineNoPrescription
Propranolol (Inderal®)MigraineCluster headachesNoPrescription
Sufentanil (Dsuvia™)Acute painNoneNoPrescription
Tapentadol (Nucynta®, Nucynta ER®)PainNonePotentiallyPrescription
Tramadol (Ryzolt™, Ultram®)PainHeadache, fibromyalgia, neuropathic painYesPrescription
Verapamil (Calan®, Isoptin®)NoneCluster headachesNoPrescription
Ziconotide (Prialt®)Chronic refractory painNeuropathic pain, chronic cancer painNoPrescription
Authors

10.3928/02793695-20190930-79

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