| ANTICONVULSANT AGENTS |
| Gabapentin (Gralise®, Neurontin®) | Off-label use | | | | Off-label use |
| Lamotrigine (Lamictal®) | | Off-label use | | Off-label use | |
| ANTIDEPRESSANT AGENTS |
| Amitriptyline (formerly Elavil®) | Off-label use | | Off-label use | Off-label use | |
| Citalopram (Celexa®) | Off-label use | Off-label use | Off-label use | Off-label use | Off-label use |
| Clomipramine HCl (Anafranil®) | Off-label use | FDA approved | Off-label use | Off-label use | Off-label use |
| Desvenlafaxine (Khedezla®, Pristiq®) | Off-label use | Off-label use | Off-label use | Off-label use | Off-label use |
| Doxepin (Adapin®, Sinequan®) | Off-label use | | Off-label use | Off-label use | Off-label use |
| Duloxetine HCl (Cymbalta®) | FDA approved | Off-label use | Off-label use | Off-label use | Off-label use |
| Escitalopram oxalate (Lexapro®) | FDA approved | Off-label use | Off-label use | Off-label use | Off-label use |
| Fluoxetine HCl (Prozac®, Prozac® WeeklyTM) | Off-label use | FDA approved | FDA approved | Off-label use | Off-label use |
| Fluvoxamine (formerly Luvox®) | Off-label use | FDA approved | Off-label use | Off-label use | FDA approved |
| Imipramine (Tofranil®) | Off-label use | | Off-label use | Off-label use | Off-label use |
| Levomilnacipran (Fetzima®) | Off-label use | Off-label use | Off-label use | Off-label use | Off-label use |
| Mirtazapine (Remeron®, Remeron SolTab®) | Off-label use | Off-label use | Off-label use | Off-label use | |
| Nortriptyline (Aventyl®, Pamelor®) | Off-label use | | Off-label use | Off-label use | |
| Paroxetine HCl (Paxil®, Paxil CR®, Pexeva®) | FDA approved | FDA approved | FDA approved | FDA approved | FDA approved |
| Sertraline HCl (Zoloft®) | Off-label use | FDA approved | FDA approved | FDA approved | FDA approved |
| Trazodone (Desyrel®, Oleptro®) | Off-label use | | | | |
| Venlafaxine HCl (Effexor®, Effexor XR®) | FDA approved | Off-label use | FDA approved | Off-label use | FDA approved |
| Vilazodone (Viibryd®) | Off-label use | | | | |
| Vortioxetine (Brintellix®) | Off-label use | Off-label use | Off-label use | Off-label use | Off-label use |
| ANTIPSYCHOTIC AGENTS | | | | | |
| Quetiapine (Seroquel®, Seroquel XR®) | Off-label use | Off-label use | Off-label use | Off-label use | |
| Trifluoperazine (formerly Stelazine®) | FDA approved | | | Off-label use | |
| BENZODIAZEPINE AGENTS | | | | | |
| Alprazolam (Alprazolam Intensol®, Niravam®, Xanax®, Xanax XR)a | FDA approved | | FDA approved | | Off-label use |
| Chlordiazepoxide (Librax®, Limbitrol®, Limbitrol® DS)b | FDA approved | | Off-label use | | Off-label use |
| Clonazepam (Klonopin®)b | Off-label use | Off-label use | FDA approved | | Off-label use |
| Clorazepate (formerly Tranxene®) | FDA approved | | Off-label use | | Off-label use |
| Diazepam (Diazepam Intensol®, Valium®)b | FDA approved | | Off-label use | | Off-label use |
| Lorazepam (Ativan®, Lorazepam Intensol®)b | FDA approved | | Off-label use | | Off-label use |
| Oxazepam (formerly Serax®)a,b | FDA approved | | Off-label use | | Off-label use |
| NONBENZODIAZEPINE AGENTS |
| Buspirone HCl (formerly Buspar®) | FDA approved | Off-label use | Off-label use | | Off-label use |
| Diphenhydramine (Benadryl®) | Off-label use | | | | |
| Hydroxyzine (Anxanil®, Vistaril®)b | Off-label use | | | | |
| Meprobamate (formerly Miltown®) | FDA approved | | | | |
| Propranolol (formerly Inderal®) | Off-label use | | Off-label use | Off-label use | Off-label use |