In the Journals

Late menopause may lower type 2 diabetes risk

Later age at menopause was associated with lower risk for type 2 diabetes, according to a meta-analysis published in Primary Care Diabetes.

“In view of the inconsistent results of previous studies, we performed a dose-response meta-analysis of all available data from cohort studies of age at menopause and risk of type 2 diabetes,” Chunmei Guo, of the department of epidemiology and health statistics at Zhengzhou University in the People’s Republic of China, and colleagues wrote.

Woman having a hot flash 

Later age at menopause was associated with lower risk for type 2 diabetes, according to a meta-analysis published in Primary Care Diabetes.

Source:Adobe

The meta-analysis included six studies, with a total of 267,284 women and 19,654 cases of type 2 diabetes. The average age of the women ranged from 56.1 to 66.9 years, and the longest follow-up period was 12.2 years.

According to Guo and colleagues, the pooled RR for type 2 diabetes was 0.64 (95% CI, 0.44-0.94) when comparing the latest with the earliest category of age at menopause. The risk for type 2 diabetes was reduced by 10% (RR = 0.9; 95% CI, 0.84–0.98) for each 5-year increment in age at menopause.

“Our meta-analysis differs from previous original studies because we based [ours] on cohort studies and larger sample size, which increased the reliability and accuracy of the effect estimates, and further quantified the dose-response association between age at menopause and type 2 diabetes,” Guo and colleagues wrote. – by Janel Miller

Disclosures: The authors report no relevant financial disclosures.

 

Later age at menopause was associated with lower risk for type 2 diabetes, according to a meta-analysis published in Primary Care Diabetes.

“In view of the inconsistent results of previous studies, we performed a dose-response meta-analysis of all available data from cohort studies of age at menopause and risk of type 2 diabetes,” Chunmei Guo, of the department of epidemiology and health statistics at Zhengzhou University in the People’s Republic of China, and colleagues wrote.

Woman having a hot flash 

Later age at menopause was associated with lower risk for type 2 diabetes, according to a meta-analysis published in Primary Care Diabetes.

Source:Adobe

The meta-analysis included six studies, with a total of 267,284 women and 19,654 cases of type 2 diabetes. The average age of the women ranged from 56.1 to 66.9 years, and the longest follow-up period was 12.2 years.

According to Guo and colleagues, the pooled RR for type 2 diabetes was 0.64 (95% CI, 0.44-0.94) when comparing the latest with the earliest category of age at menopause. The risk for type 2 diabetes was reduced by 10% (RR = 0.9; 95% CI, 0.84–0.98) for each 5-year increment in age at menopause.

“Our meta-analysis differs from previous original studies because we based [ours] on cohort studies and larger sample size, which increased the reliability and accuracy of the effect estimates, and further quantified the dose-response association between age at menopause and type 2 diabetes,” Guo and colleagues wrote. – by Janel Miller

Disclosures: The authors report no relevant financial disclosures.