In the Journals

Opioid, benzodiazepine coprescription slightly declines after boxed warning

September 20, 2019
The FDA boxed warning issued in 2016 highlighting the risks of coprescribing opioids and benzodiazepines was linked to a decrease in the number of…

Feature

Risk for neural tube defects from dolutegravir lower than previously thought

Infectious Diseases in Children, September 2019
According to results from the ongoing Tsepamo study in Botswana, infants born to women who took the integrase inhibitor dolutegravir for HIV…

Novartis stops distribution of Zantac

September 19, 2019
Zantac manufacturer Novartis has stopped the distribution of its heartburn medication across all available markets, including the United States and…

In the Journals

Polypill strategy effective in US socioeconomically disadvantaged population

September 18, 2019
Among a U.S. population of socioeconomically disadvantaged adults, a polypill-based strategy was associated with greater reductions in systolic BP…

Meeting News

Ponesimod more effective than existing treatment for relapsing MS, study finds

September 13, 2019
Ponesimod, an investigational selective S1P1 receptor modulator, was more effective at treating adults with relapsing multiple sclerosis than…

Feature

Purdue Pharma tentatively settles opioid lawsuits, others still pending

September 12, 2019
Oxycontin manufacturer Purdue Pharma recently reached a tentative agreement with many of the thousands of plaintiffs involved in a multidistrict…

In the Journals

Postoperative opioid prescription fill rate 7 times higher in US, Canada vs. Sweden

September 12, 2019
The rate of postoperative opioid prescriptions filled was seven times higher in the United States and Canada than in Sweden, according to a study…

Breaking News

‘Progress being made’ in opioid epidemic, CDC says

September 12, 2019
A CDC spokesperson said provisional data and other reports signify that “progress is being made” in the opioid epidemic. The turnaround…

In the Journals

Comprehensive prescription drug monitoring program mandates reduce opioid prescribing in hospitals

September 10, 2019
State mandates that require both prescribers and dispensers to enter and use prescription drug monitoring programs led to greater reductions in…

Meeting News

Xarelto monotherapy noninferior to combination therapy for CV events

September 10, 2019
Xarelto monotherapy was noninferior to Xarelto plus an antiplatelet agent in regards to CV events and death from any cause in patients with atrial…

Feature

Q&A: Benefits, harms of estrogen therapy in women who had ovaries removed

September 9, 2019
For women who had a hysterectomy and their ovaries removed, estrogen therapy was associated with long-term benefits if the therapy began before the…

Meeting News

Community-based intervention could significantly reduce CVD risk

September 6, 2019
A community-based intervention that included nonphysician health workers, PCPs and patient family members significantly reduced CVD risk and…

ACR: CVS-Aetna merger threatens efforts to lower drug costs

September 6, 2019
The American College of Rheumatology issued a warning on Friday that a U.S. District Court judge’s decision to allow CVS Health Corp to merge…

Meeting News

Older patients do not benefit from aspirin for CVD prevention

September 5, 2019
Taking aspirin for primary prevention of cardiovascular disease does not benefit older adults, according to findings from the ASPREE trial presented…

In the Journals

Evidence does not support antipsychotics for prevention, treatment of delirium in hospitals

September 5, 2019
Haloperidol and second-generation antipsychotics should not be routinely used to prevent or treat delirium in hospitalized patients based on evidence…

Feature

Experts discuss future opioid lawsuit strategies, lawsuits’ impact on manufacturers

September 4, 2019
Last month, Johnson & Johnson was ordered to pay more than $572 million in damages for its role in the opioid epidemic in Oklahoma. Purdue Pharma…

In the Journals

Access barriers, medication acceptability hinder long-term buprenorphine use

September 3, 2019
Only about 10% of participants with opioid use disorder used buprenorphine treatment over a 2-year follow-up period mainly due to issues with access…

Xofluza reduces risk for flu by 86% in household contacts

September 3, 2019
Xofluza significantly reduced the risk for influenza infection among children aged younger than 12 years and adults living with infected individuals…

In the Journals

Small Fournier gangrene risk with SGLT-2 inhibitors should not influence prescribing decisions

September 3, 2019
For men with type 2 diabetes, the small increased risk for Fournier gangrene associated with SGLT-2 inhibitor treatment should not dissuade…

Meeting News

Aspirin fails to benefit elderly patients for CVD prevention

August 31, 2019
PARIS — Aspirin did not benefit older patients for the primary prevention of CVD, according to a new analysis from the ASPREE trial presented…