NEW ORLEANS — Healthy men who received either a 200-mg or 400-mg modified testosterone pill daily experienced an effect that mirrored effective contraception and also maintained their sexual function, according to study data presented at the Endocrine Society annual meeting.
Researchers said the pill, known as 11-beta-methyl-19-nortestosterone dodecyl carbonate, was tested in a randomized, placebo-controlled trial for 28 days and was well-tolerated. There were no serious adverse events tied to its use, and no men participating in the study discontinued the drug.
The modified testosterone pill reviewed here is just one of several male contraceptive options via different mechanisms that is currently under development, researchers said.
More Healio coverage of this study can be found by clicking here. – by Janel Miller and Regina Schaffer
Reference: Wang C. SUN-LB042. The novel androgen 11-methyl-19-nortestosterone dodecylcarbonate (11-beta-MNTDC) effectively suppresses gonadotropins andtestosterone in healthy men: A potential oral male hormonal contraceptive. Presented at: The Endocrine Society Annual Meeting; March 23-26, 2019; New Orleans.
Disclosures: Wang reports she has served as a research investigator for Antares, Clarus, TesoRX and the Testosterone Replacement Therapy Manufacturers Consortium.