Statins tied to greater risk for new-onset diabetes — top stories in endocrinology

Two different studies regarding statins — one that indicated their use raised the risk for new-onset diabetes and a second that concluded high-dose statin therapy may heighten fracture risk — were the top stories in endocrinology last week.

Read more about these studies’ findings and other top stories in endocrinology.

Statin use raises risks for new-onset diabetes, skin infections

The use of statins for as little as 91 days is associated with an increased risk for skin infections via diabetogenic and nondiabetogenic mechanisms, according to findings published in the British Journal of Pharmacology. Read more.

High-dose statin therapy may heighten fracture risk

Individuals prescribed high-dose statin therapy to manage cardiovascular risk are more likely to receive a diagnosis of osteoporosis compared with those prescribed a low-dose statin or no therapy, according to findings from a database analysis published in Annals of Rheumatic Diseases. Read more.

Mild activity, walking reduce hip fracture risk for postmenopausal women

Regular, weekly physical activity such as walking and yard work can lower the risk for hip or total fracture among postmenopausal women, according to findings published in JAMA Network Open. Read more.

Type 2 diabetes tied to greater risk for vertebral, nonvertebral fractures

Adults with type 2 diabetes are 55% more likely to sustain an incident vertebral fracture compared with adults without diabetes, with vertebral fracture history further raising the risk for experiencing a nonvertebral fracture, according to findings published in Diabetes Care. Read more

Thyroid over-replacement may increase atrial fibrillation, stroke risks

Among a large cohort of adults prescribed thyroid hormone replacement therapy, those with low thyroid-stimulating hormone levels had more atrial fibrillation and strokes, according to study data presented at the American Thyroid Association annual meeting in Chicago. Read more.

Two different studies regarding statins — one that indicated their use raised the risk for new-onset diabetes and a second that concluded high-dose statin therapy may heighten fracture risk — were the top stories in endocrinology last week.

Read more about these studies’ findings and other top stories in endocrinology.

Statin use raises risks for new-onset diabetes, skin infections

The use of statins for as little as 91 days is associated with an increased risk for skin infections via diabetogenic and nondiabetogenic mechanisms, according to findings published in the British Journal of Pharmacology. Read more.

High-dose statin therapy may heighten fracture risk

Individuals prescribed high-dose statin therapy to manage cardiovascular risk are more likely to receive a diagnosis of osteoporosis compared with those prescribed a low-dose statin or no therapy, according to findings from a database analysis published in Annals of Rheumatic Diseases. Read more.

Mild activity, walking reduce hip fracture risk for postmenopausal women

Regular, weekly physical activity such as walking and yard work can lower the risk for hip or total fracture among postmenopausal women, according to findings published in JAMA Network Open. Read more.

Type 2 diabetes tied to greater risk for vertebral, nonvertebral fractures

Adults with type 2 diabetes are 55% more likely to sustain an incident vertebral fracture compared with adults without diabetes, with vertebral fracture history further raising the risk for experiencing a nonvertebral fracture, according to findings published in Diabetes Care. Read more

Thyroid over-replacement may increase atrial fibrillation, stroke risks

Among a large cohort of adults prescribed thyroid hormone replacement therapy, those with low thyroid-stimulating hormone levels had more atrial fibrillation and strokes, according to study data presented at the American Thyroid Association annual meeting in Chicago. Read more.