New data published in JAMA Network Open show that PCSK9 genetic variants were not associated with the risk for sepsis or sepsis outcomes in patients hospitalized with infection.
Of 10,922 white adults with infection who had genotypes available for PCSK9 functional variants seen at Vanderbilt University Medical Center (mean age, 60.1 years; 48.5% women), 3,391 developed sepsis, 835 developed cardiovascular failure and 366 died while in the hospital.
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