Pediatrics

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Concerns, controversies in pediatric IBD persist in era of biologics

Infectious Diseases in Children, December 2017

The treatment of pediatric inflammatory bowel disease has been revolutionized by the advent of biologic therapies, which have been shown to effectively treat symptoms, induce mucosal healing, and reverse growth impairment in many patients. However, experts continue to debate the positioning of biologics in IBD, and are seeking ways to better understand how to deliver optimal treatment to children affected by the disease.

Pediatric IBD rates are on the rise globally, and the 20% to 30% of patients with IBD onset before age 20 years often have more extensive, severe and complicated disease compared with those whose disease presents in adulthood. According to experts interviewed by Infectious Diseases in Children, early treatment with biologics provides newfound hope for preventing these complications, though many factors must be considered when choosing an initial therapy for children. Unfortunately, despite their availability and impact, several barriers prevent the use of biologics as first-line therapies.

What's Your Diagnosis?

15-year-old male presents with recurrent abscesses in both axillae

Infectious Diseases in Children, December 2017
James H. Brien, DO
A 15-year-old male presents to your office with recurrent abscesses in both axillae for the last 8 months. The lesions begin as red bumps that go on to form abscesses…
Spot the Rash

A 5-year-old male with 4-month history of rash on cheek

Infectious Diseases in Children, December 2017
Aditi Murthy, MD; Marissa J. Perman, MD
A 5-year-old male presented to a dermatology clinic with a 4-month history of rash on the left cheek. The parents reported that they initially noted small bumps on his…
In the Journals

Maternal RA linked to thyroid disease, epilepsy in children

December 13, 2017
Children born to mothers with rheumatoid arthritis have an increased risk for chronic diseases, including thyroid disease, epilepsy and rheumatoid arthritis, during…
In the Journals

Lyme disease diagnosis based on clinician suspicion often inaccurate

December 13, 2017
Clinician suspicion had minimal accuracy in differentiating between children with and without Lyme disease who presented to the ED, according to findings published in…
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Original Article

Time and Factors Affecting the Direction of Re-drift in Essential Infantile Esotropia

Journal of Pediatric Ophthalmology and Strabismus
Online Advanced Release, November 14, 2017
To investigate the development pattern and related factors of postoperative re-drift in infantile esotropia. A total of…
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CME

Pediatric Rheumatology: June 2015

Keck School of Medicine of USC and Pediatric Annals

Of all the areas of pediatric practice, none can seem more daunting or require a higher index of suspicion than…
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Resource Centers
American Academy of Pediatrics National Conference & Exhibition

American Academy of Pediatrics National Conference & Exhibition

Video
Meeting News

VIDEO: ‘Great need’ for new antivirals to combat H7N9

October 17, 2017
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