Pharmacology Consult

Continued pertussis outbreaks call vaccine effectiveness into question

Infectious Diseases in Children, June 2016
Edward A. Bell, PharmD, BCPS
Immunization strategies to control pertussis infection and disease in infants and children have been in use for more than 70 years, yet large…

In the Journals

Males more frequently infected with invasive pneumococcal diseases

June 13, 2016
A recent analysis of CDC surveillance data suggested that male invasive pneumococcal disease rates were significantly greater than those of females…

In the Journals

Respiratory viruses common among children with cancer experiencing fever, neutropenia

June 9, 2016
Recent findings published in Pediatric Infectious Disease Journal showed that respiratory viral infections were found in 46% of children with cancer…

In the Journals

New pneumococcal serotypes colonize nasopharynx since PCV13 introduction

June 7, 2016
New serotypes of pneumococcus have begun to colonize the nasopharynx of children since the introduction of the PCV13 vaccine in 2010, according to…

In the Journals

Tdap administration safe during pregnancy

June 1, 2016
Recent research in Human Vaccines and Immunotherapeutics determined that the use of Tdap vaccine during pregnancy was safe for women and…

FDA News

FDA expands indication of Teflaro for pediatric patients with CABP, ABSSSIs

May 31, 2016
The FDA has expanded the indication for Teflaro, an injectable antibiotic in the cephalosporin class, to treat pediatric patients aged 2 months to 18…

Meeting News Coverage

Ships’ fuel oil exhaust may impact lungs of children in California

May 25, 2016
Nickel and vanadium found in burning fuel oil from ships off the Southern California coast might damage the developing lungs of children, according…

In the Journals

Antibody responses to F, G proteins in RSV show unlinked evolution

May 13, 2016
Recent findings published in PLoS Pathogens showed that the anti-F and anti-G responses of respiratory syncytial virus had an unlinked evolution. In…

Meeting News Coverage

Pediatric providers report adherence to IDSA CAP guidelines

May 10, 2016
BALTIMORE — Pediatric health care providers reported increased adherence to appropriate empiric therapy after the Infectious Diseases Society…

In the Journals

Pediatric respiratory infection increases risk for type 1 diabetes

May 6, 2016
The development of type 1 diabetes by age 8 years was linked to recurrent viral respiratory tract infections in the first 6 months of age, according…

Meeting News Coverage

Preterm infants hospitalized for RSV face increased risk for ICU admission

May 3, 2016
BALTIMORE — Recent data from the SENTINEL1 study showed that preterm infants hospitalized for respiratory syncytial virus are at increased risk…

Meeting News Coverage

One in six children hospitalized for bronchiolitis tested positive for marijuana exposure

May 3, 2016
BALTIMORE — One in six children hospitalized for bronchiolitis in Colorado had been exposed to marijuana, according to data presented at the…

Meeting News Coverage

Hospitalizations longer, costlier for children with aspiration pneumonia

May 3, 2016
BALTIMORE — Children diagnosed with aspiration pneumonia had longer and costlier hospitalizations than those with community-acquired pneumonia…

Meeting News Coverage

Hospital factors associated with increased LOS, costs for infants with bronchiolitis

May 2, 2016
BALTIMORE — Location-teaching status and region were linked to an increased length of stay and cost for infants hospitalized with…

Meeting News Coverage

Pertussis incidence significantly declines in New York after legislation

April 30, 2016
BALTIMORE — Data presented at the Pediatric Academic Societies Meeting showed that pertussis incidence decreased by more than 50% after the…

In the Journals

Human metapneunmovirus shows distinct seasonality vs. RSV, flu

April 26, 2016
Recent findings published in Pediatrics showed that human metapneumovirus, compared with influenza and respiratory syncytial virus, demonstrated…

In the Journals

Viral URI, other factors increase risk for AOM in infants

April 22, 2016
Recent research in Pediatrics indicated that viral upper respiratory tract infections, pathogenic bacterial colonization and lack of breast-feeding…

In the Journals

Blood-based signature predicts tuberculosis in healthy patients

April 22, 2016
Researchers in this study have developed a blood-based signature from following individuals with Mycobacterium tuberculosis that can predict active…

In the Journals

ICU admittance more common among children with neurologic disorders, CAP

April 18, 2016
A study published in The Journal of Pediatrics reported that children with neurologic disorders and hospitalized with community-acquired pneumonia…

In the Journals

Curcumin controls MTB infection in model

April 14, 2016
Researchers in this study showed an ability to control Mycobacterium tuberculosis in a macrophage infection model using curcumin, according to…