At Issue

Pertussis vaccines and the next steps in development

Infectious Diseases in Children, January 2018
Infectious Diseases in Children asked C. Buddy Creech, MD, MPH, associate professor of pediatrics, division of pediatric infectious diseases, and

Cover Story

Pertussis increase attributed to waning vaccine immunity

Infectious Diseases in Children, January 2018
Since the 1940s, the diphtheria, tetanus and pertussis vaccine has been widely available to combat the transmission and development of pertussis…

FDA committee fails to recommend Linhaliq for chronic lung infection

January 12, 2018
Aradigm Corporation recently announced that the FDA’s Antimicrobial Drugs Advisory Committee did not recommend approval for Linhaliq to treat…

In the Journals

Positive LAM results predict mortality in children with HIV

January 12, 2018
Children with HIV in Kenya whose urine samples tested positive for lipoarabinomannan, or LAM — a biomarker of tuberculosis — had a nearly…

FDA expands opioid safety warnings on cough, cold medications

January 11, 2018
The FDA is attempting to combat pediatric exposure to cough and cold medicines containing opioids by requiring changes to safety labeling on these…

In the Journals

Study supports narrow-spectrum antibiotics for pediatric respiratory infections

December 19, 2017
Narrow-spectrum antibiotics are preferable to broad-spectrum antibiotics for treating most children with acute respiratory tract infections…

In the Journals

Probiotics, xylitol gum ineffective against sore throat

December 18, 2017
Probiotic capsules and xylitol chewing gum were ineffective in managing pharyngitis symptoms, according to results from a randomized controlled trial…

Diphtheria spreading among Rohingya refugees

December 8, 2017
Diphtheria is quickly spreading among Rohingya refugees in Cox’s Bazar, Bangladesh, according to WHO. As of Dec. 6, more than 110 suspected…

H3N2, known to evade vaccine, is predominant flu strain in US

December 8, 2017
Influenza A(H3N2) — a strain known for evading the seasonal influenza vaccine and causing relatively severe illness — has been the…

In the Journals

One dose of pneumococcal vaccine plus booster effective in UK study

December 5, 2017
A single dose plus a booster of the 13-valent pneumococcal conjugate vaccine was equal or superior to the current two-dose plus booster schedule for…

Genetic mutation in FluMist could be altered to restore effectiveness

December 3, 2017
Johns Hopkins University researchers said they discovered a genetic mutation in the nasal spray influenza vaccine that could be altered to restore…

In the Journals

Many health care workers do not know correct influenza precautions

December 2, 2017
In a small survey conducted at a St. Louis hospital, many health care personnel could not describe the correct transmission-based precautions for…

In the Journals

Macrolide antibiotics fail to provide additional benefit for children with pneumonia

November 13, 2017
For children hospitalized with community-acquired pneumonia, there is no significant difference between treatment with beta-lactam monotherapy and

Disneyland cooling towers linked to Legionnaires’ disease outbreak

November 13, 2017
Disney shut down two cooling towers at its Disneyland Park in Anaheim, California, after health officials notified the company about a cluster of…

Top stories to read on World Pneumonia Day

November 12, 2017
Although pneumonia can be prevented by immunization, good hygiene practices and adequate nutrition, it accounted for the deaths of more than 920,000…

HPV vaccine prevents incurable childhood respiratory disease

November 9, 2017
For the first time, researchers have found evidence that the HPV vaccine prevents an incurable respiratory infection in children. According to…

As Madagascar plague outbreak loosens grip, concerns linger

November 1, 2017
An outbreak of plague in Madagascar has started to decline in recent weeks, with 12 previously affected districts reporting no new confirmed or…

In the Journals

Investigational acellular pertussis vaccine effective in adolescents, approved in Thailand

October 31, 2017
Recent phase 2/3 data showed that a new recombinant acellular pertussis booster vaccine administered alone or in combination with tetanus and…


WHO: Ending TB will take greater political commitment

October 30, 2017
Health experts warned that progress to end tuberculosis has stalled and that greater political commitment is needed to address the burden of the…

In the Journals

Influenza antivirals underused in high-risk outpatients

October 30, 2017
New research findings from five recent influenza seasons showed that influenza antivirals were underused in outpatients at a high risk for…