FDA News

FDA CLIA-waives BinaxNOW influenza rapid test

February 28, 2019
Abbott’s reformulated lateral flow influenza assay has been waived by the FDA under the Clinical Laboratory Improvement Amendments, or CLIA…

In the Journals

Weight-age score predicts effectiveness of childhood TB therapy

February 25, 2019
Weight change early in therapy predicted outcomes of childhood tuberculosis therapy, according to study results published in the Journal of the

In the Journals

Reduced efficacy from repeat flu vaccination depends on vaccine type, strain

February 20, 2019
Repeat immunization with inactivated influenza vaccine appears to reduce children’s antibody responses to influenza strains A(H1N1)pdm09 and B…

In the Journals

Nitazoxanide not beneficial for treatment of severe acute respiratory illness

February 19, 2019
Adding nitazoxanide to standard of care for the treatment of children and adults with severe acute respiratory infections was safe, but it did not…

In the Journals

Rapid flu tests reduce antibiotic prescriptions, additional visits

February 19, 2019
Children who have confirmed influenza receive fewer antibiotics in the 10 days after diagnosis and were less likely to use further health care…

Viral, bacterial diagnostics bolster antimicrobial stewardship

Infectious Diseases in Children, February 2019
Numerous viral and bacterial respiratory illnesses have overlapping symptoms. In many cases, it can be difficult for pediatricians to determine what…

In the Journals

Palivizumab not effective treatment for RSV bronchiolitis

February 18, 2019
IV palivizumab, a monoclonal antibody to respiratory syncytial virus, or RSV, did not appear to help or harm infants with RSV-positive bronchiolitis…

In the Journals

Parents collect respiratory samples earlier in illness than HCWs

Infectious Diseases in Children, March 2019
Parents in Australia who were trained to collect nasal swabs did so nearly 2 days sooner after their children’s symptoms of an acute…

In the Journals

Parents collect respiratory samples earlier in illness than HCWs

February 15, 2019
Parents in Australia who were trained to collect nasal swabs did so nearly 2 days sooner after their children’s symptoms of an acute…

Causes of 2014 EV-D68 outbreak still unknown

February 13, 2019
Researchers are still searching for the reasons behind a 2014 outbreak of enterovirus D68, or EV-D68, which affected more than 1,100 people…

In the Journals

BCG vaccine scars tied to decline in infant mortality

February 13, 2019
Scarring caused by bacillus Calmette-Guérin, or BCG, vaccine in both mothers and infants was associated with a significant decrease in infant…

In the Journals

Educational intervention reduces antibiotic prescribing for childhood URTIs 1 year later

February 12, 2019
An educational intervention program for Chinese primary care doctors was effective in reducing antibiotic prescriptions for childhood upper…

Measles cases in Europe tripled in 2018, WHO says

February 7, 2019
Nearly 83,000 cases of measles were reported in Europe last year — more than triple the amount reported in 2017 and 15 times as many cases as…

In the Journals

PCV13 reduces CAP in France more than 5 years later

February 6, 2019
Vaccination with the 13-valent pneumococcal conjugate vaccine has consistently decreased the rate of community-acquired pneumonia among French…

In the Journals

LAIV added to immunization schedule

February 5, 2019
The childhood and adolescent immunization recommendations for 2019 have been updated to include the use of a live-attenuated intranasal influenza…

Washington measles outbreak declared a state of emergency

January 28, 2019
A state of emergency has been declared in Clark County, Washington, after 34 people were infected with measles during a statewide outbreak. The…

70% of infants given antibiotics for bronchiolitis had no bacterial coinfection

January 24, 2019
A quarter of children aged younger than 2 years with bronchiolitis who visited U.S. EDs between 2007 and 2015 received antibiotics, even though 70%…

Pharmacology Consult

Not all 3GCs are created equal: Oral antibiotic selection in pediatric pneumococcal infections

Infectious Disease News, January 2019
Leah Molloy, PharmD
Community-acquired pneumonia (CAP), otitis media (OM) and acute bacterial rhinosinusitis (ABRS) are common childhood illnesses. Although OM is more…

In the JournalsPerspective

Viral pathogen presence changes during course of acute sinusitis symptoms

January 22, 2019
Upper respiratory infections, or URIs, are more common among children who develop acute sinusitis, according to research published in Clinical

Parents understand cold prevention; most still use unproven strategies

Infectious Diseases in Children, March 2019
Nearly all parents participating in a nationally representative poll follow evidence-based cold prevention strategies for their children, including…