November 13, 2017
Alanine aminostransferase maintained better levels at mid-childhood when children took in a higher amount of the alpha-tocopherol isoform of vitamin E at early childhood, according to data published in Hepatology.
“Early and mid-childhood could be key windows of opportunity to prevent rising ALT levels. Moreover, identifying protective factors against elevated ALT levels could inform future interventions to prevent pediatric [non-alcoholic fatty liver disease (NAFLD)],” Jennifer A. Woo Baidal, MD, MPH, from the division of pediatric gastroenterology, hepatology and nutrition at Columbia University Medical Center and colleagues wrote. “Vitamin E is a prime candidate for protection against development of NAFLD. ... Identifying the prospective association of alpha-tocopherol intake during early childhood with later ALT levels could inform future efforts to prevent liver damage in children.”