Richard J. Blandau (Editor) MORPHOGENESIS AND MALFORMATION OFTHE SKIN New York: Alan R. Liss. Inc., 1981 286 pp., $44.00.
The primary value of a workshop is to afford an opportunity for laboratory scientists and physicians to explore a subject in depth, to direct attention to significant gaps that remain in our knowledge of the subjects discussed, and to awaken more interest and further investigation and research in the field under review.
This book, a review of the proceedings of the Sixth International Workshop on Morphogenesis and Malformation sponsored by the March of Dimes Birth Defects Foundation at Lake Wilderness, Washington, September 1980, does much to further this premise. It reviews current information on the ultrastructure of skin through the embryonic, fetal, premature, neonatal, and adult periods of life; the control of differentiation of epidermal structures; mechanical factors in the development of the skin and its derivatives; the biology of pigmentation; disorders associated with immunogenetic deficiencies; disorders of connective tissue metabolism; neurofibromatosis; epidermolysis hullosa; the ichthyoses; muco polysaccha rid oses and mucolipidoses; premature aging syndromes on the skin; and the current status of prenatal diagnosis of inherited cutaneous diseases.
Although these discussions offer insight into the development, structure, and function of the skin, they also highlight the fact that much remains to be learned and these areas of research require far more investigation. This book is recommended for physicians interested in cutaneous morphogenesis and its relationship to cutaneous malformations, thus making it a valuable reference book belonging in dermatologie and research libraries. Primarily aimed at scientists and dermatologists interested in inherited cutaneous disorders, it has limited value for the average practicing pediatrician.