Abnormal glucose tolerance, especially prediabetes, was highly prevalent among children and adolescent patients with established nonalcoholic fatty liver disease, according to a recently published study.

Although central adiposity is the factor most strongly associated with progression from NAFLD to nonalcoholic steatohepatitis, Valerio Nobili, MD, from the Bambino Gesù Hospital in Italy, and colleagues explained that children with abnormal glucose tolerance also have an increased risk for NASH.