Although patients who undergo elective total joint arthroplasty after organ transplantation experienced a relatively higher risk of perioperative medical complications, reoperation and periprosthetic infection, clinical outcome measures and patient-reported satisfaction were very high, according to study results.
Researchers retrospectively reviewed charts for all patients who underwent primary total joint arthroplasty (TJA) following kidney, liver, cardiac or lung transplantation between 1999 and 2012 and identified 76 TJAs in 56 solid organ transplant patients. The researchers collected data on acute perioperative courses and validated functional outcome measures, including Harris Hip score (HHS), Knee Society scores (KSS) and VAS scores.
Study results showed a high rate of perioperative medical complications and increased hospital length of stay in both total hip and knee arthroplasty (THA, TKA) patients. Among the THA group, reoperation rates for any reason were present in the kidney and liver groups, whereas all cohorts had a consistent rate of reoperation among patients who underwent TKA.
The researchers found a significant increase in HHS from 43.7 preoperatively to 87.7 postoperatively, as well as significant increases in objective KSS from 53.6 preoperatively to 90.7 postoperatively and functional KSS from 60.5 preoperatively to 84.3 postoperatively.
Despite the high rates of complication, patients in both THA and TKA groups reported good or excellent outcomes, according to the researchers.
Disclosure: See the study for full financial disclosures.