In the acute postoperative period, recently published results showed serum D-dimer was an ineffective screening test for the diagnosis of symptomatic deep venous thrombosis in patients undergoing total joint arthroplasty.
Researchers measured serum D-dimer preoperatively, perioperatively and postoperatively at 2 weeks and 6 weeks in 177 adult patients aged 40 years to 88 years who underwent primary total hip arthroplasty (THA) or total knee arthroplasty (TKA) with a Charlson Comorbidity Index of less than three.
Among both THA and TKA groups, results showed D-dimer measurements peaked at 2 weeks postoperatively and resolved at the 6-week time point by 54.3% for patients in the TKA group and by 76.6% for patients in the THA group. Researchers found 92% of patients who underwent THA and 100% of patients who underwent TKA had serum D-dimer measurements higher than the 0.40 μg/mL institutional threshold for a positive quantitative test at 6 weeks postoperatively. Neither groups reported symptomatic deep venous thrombosis during the study period, according to results. – by Casey Tingle
Disclosures: An reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.