A single injection of either leukocyte-rich platelet-rich plasma or leukocyte-poor platelet-rich plasma combined with an exercised-based rehabilitation program was not more effective than saline for patients with patellar tendinopathy, according to recently published results.
Researchers assessed 57 athletes with patellar tendinopathy for 6 months or more. They randomly assigned 19 patients to receive an injection with leukocyte-rich platelet-rich plasma (LR-PRP), 19 patients to receive leukocyte-poor PRP (LP-PRP) and 19 patients to receive saline. After patients received the injection, they had 6 weeks of supervised rehabilitation. At 6 and 12 weeks and at 6 and 12 months, outcome measures assessed included Victorian Institute of Sport Assessment (VISA-P), pain during activity and global rating of change. The primary outcome was the VISA-P at 12 weeks.
At 12 weeks, study retention was 93%. At 1 year, it was 79%.
Among the three treatment groups, no differences were seen in the mean change in VISA-P, pain or global rating of change at 12 weeks. The mean VISA-P score for the LR-PRP, LP-PRP and saline groups after 1 year for was 58, 71 and 80, respectively. The mean pain score was 4 for patients who received LR-PRP, was 2.4 for those who received LP-PRP and was 2 for those who received saline. The global rating of change for patients who received LR-PRP, LP-PRP and saline was 4.7, 5.6 and 5.7, respectively. – by Monica Jaramillo
Disclosures: Scott reports a grant from the American Orthopaedic Society for Sports Medicine for research expenditures. Please see the full study for a list of all other authors’ relevant financial disclosures.