In the Journals

Study highlights factors, incidence of additional lesions in axial spine for patients with chordomas

Results from this retrospective review of data for 42 patients demonstrated 16.7% of patients with chordomas had additional lesions in the axial spine.

“It is unclear whether these represent metastases, synchronous primary chordomas or notochordal remnant tissue,” the researchers wrote. “Screening imaging of the axial spine may reveal additional lesions, in particular, in subjects with pulmonary metastases.”

Researchers retrospectively reviewed the medical records of 42 patients with chordomas that were histologically confirmed. All patients had complete axial spine imaging and 42.9% of patients were female. Investigators collected data including patient age at diagnosis; sex; race/ethnicity; chordoma size, location and type; and presence or absence of pulmonary metastases. Risk factors for additional lesions in the axial spine were determined with univariate and multivariate logistic regression models.

Results showed 16.7% of patients had additional lesions in the axial spine. Investigators noted significant predictors for additional lesions did not include age, sex, chordoma size and chordoma subtype; however, pulmonary metastases were a significant predictor for additional lesions. by Monica Jaramillo

 

Disclosures: Sebro reports no relevant financial disclosures. Please see the full study for a list of all other author’s relevant financial disclosures.   

 

Results from this retrospective review of data for 42 patients demonstrated 16.7% of patients with chordomas had additional lesions in the axial spine.

“It is unclear whether these represent metastases, synchronous primary chordomas or notochordal remnant tissue,” the researchers wrote. “Screening imaging of the axial spine may reveal additional lesions, in particular, in subjects with pulmonary metastases.”

Researchers retrospectively reviewed the medical records of 42 patients with chordomas that were histologically confirmed. All patients had complete axial spine imaging and 42.9% of patients were female. Investigators collected data including patient age at diagnosis; sex; race/ethnicity; chordoma size, location and type; and presence or absence of pulmonary metastases. Risk factors for additional lesions in the axial spine were determined with univariate and multivariate logistic regression models.

Results showed 16.7% of patients had additional lesions in the axial spine. Investigators noted significant predictors for additional lesions did not include age, sex, chordoma size and chordoma subtype; however, pulmonary metastases were a significant predictor for additional lesions. by Monica Jaramillo

 

Disclosures: Sebro reports no relevant financial disclosures. Please see the full study for a list of all other author’s relevant financial disclosures.