Recently published results showed the most common causes of failure in medial unicompartmental knee arthroplasty included aseptic loosening and osteoarthritis progression.
In a search of PubMed, EMBASE and Cochrane databases and annual registries, researchers identified 37 cohort studies and two registry-based studies that reported either more than 25 unicompartmental knee arthroplasty (UKA) failures or early, midterm or late failures.
Researchers identified 3,967 overall failures, 388 time-dependent failures and 1,305 implant design failures. Results showed aseptic loosening and progression of osteoarthritis (OA) were the most common modes of failure at 36% and 20%, respectively. Aseptic loosening (25%), progression of OA (20%), bearing dislocation (17%), pain (8%), infection (7%) and tibial subsidence (7%) were identified as the most common reasons for early failures, according to results. Researchers also identified progression of OA as the most common cause of midterm (38%) and late failures (40%), and aseptic loosening (29%) and polyethylene wear (10%) as the most common modes of failure in the late phase.
When it came to fixed-bearing and mobile-bearing failures, results showed instability and polyethylene wear were more common failure modes for fixed-bearing implants, while unexplained pain and bearing dislocation were more common failure modes for mobile-bearing implants. – by Casey Tingle
Disclosures: van der List reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.