In the Journals

Study cites physical parameters that correlate with increased complication rates after TKA

Following total knee arthroplasty, investigators found increasing BMI, body surface area, body mass and height strongly correlated with rates of revision, aseptic loosening and other common complications.

Researchers used prospectively collected data from a total joint registry from a single institution to assess 22,243 knees in 16,106 patients who were treated with primary TKA between 1985 and 2012. Revision and other common complications were evaluated with the Kaplan-Meier survival method. Cox regression analysis was used to measure other outcomes.

Investigators noted an association between increasing BMI, body surface area, body mass and height and increased risks of revision, mechanical failure and aseptic loosening after TKA. Results showed the risk of a revision surgical procedure directly correlated with each one-standard deviation increase in BMI, body surface area, body mass and height, with the association especially seen with revision for mechanical failure. The risk of failure was also associated with increasing body surface area, body mass and height in the subgroup of mechanical failure, which included a revision surgical procedure for aseptic loosening or polyethylene wear.

According to researchers, there was also an association between increasing BMI, body surface area, body mass and an increased risk of any infection. – by Monica Jaramillo

Disclosures: Christensen reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.

Following total knee arthroplasty, investigators found increasing BMI, body surface area, body mass and height strongly correlated with rates of revision, aseptic loosening and other common complications.

Researchers used prospectively collected data from a total joint registry from a single institution to assess 22,243 knees in 16,106 patients who were treated with primary TKA between 1985 and 2012. Revision and other common complications were evaluated with the Kaplan-Meier survival method. Cox regression analysis was used to measure other outcomes.

Investigators noted an association between increasing BMI, body surface area, body mass and height and increased risks of revision, mechanical failure and aseptic loosening after TKA. Results showed the risk of a revision surgical procedure directly correlated with each one-standard deviation increase in BMI, body surface area, body mass and height, with the association especially seen with revision for mechanical failure. The risk of failure was also associated with increasing body surface area, body mass and height in the subgroup of mechanical failure, which included a revision surgical procedure for aseptic loosening or polyethylene wear.

According to researchers, there was also an association between increasing BMI, body surface area, body mass and an increased risk of any infection. – by Monica Jaramillo

Disclosures: Christensen reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.