Patients who underwent total knee arthroplasty with the anatomic graduated component had nearly 95% survivorship at 25 years with little polyethylene wear, according to results.
Researchers compared the outcomes of 5,649 primary total knee arthroplasties (TKAs) in 3,735 patients (69.8% were women) with the Anatomic Graduate Component (Biomet Inc.) for 25 years to 30 years with results of patients from another institution with similar long-term follow-up. Clinical outcomes included the Knee Society score and standardized radiographs to check for loosening of the implants, and researchers also retrospectively reviewed the reason for revision surgery.
Merrill A. Ritter
Results showed an overall prosthesis survival rate of 94.2% at 25-year and 92.4% at 30-year follow-up. Researchers noted 112 failures, of which 48 implants had aseptic loosening and 25 implants had instability. Patients were substantially more likely to experience death than experience a failing prosthesis by the third decade after TKA, according to results, with a 3,811% greater risk of dying relative to failing. – by Casey Tingle
Disclosure: Ritter reports he is a paid consultant for and has stock or stock options with Iconacy Orthopedic Implants LLC and received research support from Biomet Inc.