Compared with Western ethnic groups, the incidence and prevalence of Dupuytren’s disease and the male/female ratio were significantly lower in ethnic Chinese groups, with ethnic Chinese women experiencing significantly lower age at onset, according to study results.
Searching Taiwan’s National Health Insurance Research Database, researchers identified 1,078 patients with Dupuytren’s disease who filed claims for treatment between January 2000 and December 2011. The researchers estimated age- and gender-specific incidence by dividing the incidence number by population data.
Results showed an annual incidence rate ranging from 0.39/105 to 0.63/105 for men and from 0.14/105 to 0.44/105 for women. According to trend analysis, there was a rising trend in the annual incidence from 2001 to 2011, and the prevalence rate increased steadily from 0.46/105 in 2000 to 4.52/105 in 2011.
The researchers found a significantly higher mean age onset in men vs. women, with a peak age at onset of 70 to 79 for men and 50 to 59 for women. Higher incidence rates were found among men older than 60 years vs. women.
According to the researchers, the most common comorbidities included hypertension, diabetes mellitus, hyperlipidemia, ischemic heart disease and chronic obstructive pulmonary disease. – by Casey Tingle
Disclosures: The researchers report no relevant financial disclosures.