Should orthobiologics be used in primary traumatic fracture cases?

Orthopedics Today, September 2019
The answer to the question is “yes and no.” Orthobiologics are adjuvants that are thought to improve the endogenous healing potential of the injured…

Cover Story

Standards needed for orthobiologic use in fractures

Orthopedics Today, September 2019
Some factors related to the patient or surgery, including inadequate blood flow and fracture stability, can result in fracture nonunion. However…

In the Journals

Patients with low-disease RA on tofacitinib, methotrexate can safely withdraw methotrexate

September 12, 2019
Patients with rheumatoid arthritis who achieve low disease activity with tofacitinib plus methotrexate can safely withdraw methotrexate without fear…

In the JournalsPerspective

Adalimumab well-tolerated by most children with polyarticular JIA

September 5, 2019
Adalimumab, with or without methotrexate, is well-tolerated over a period of at least 7 years among most children with polyarticular-course juvenile…

FDA News

FDA grants fast track designation to cell therapy for degenerative disk disease

August 27, 2019
The FDA has given its fast track designation to the investigational cell therapy IDCT for the treatment of degenerative disc disease. IDCT…

Meeting News

No link between TNF inhibitors, increased risk for cancer in PsA

June 14, 2019
Registry data from four European countries found no association between treatment with TNF inhibitors for psoriatic arthritis and an overall increase…


Be committed to stem cell therapy

Orthopedics Today, June 2019
Anthony A. Romeo, MD
The promise of stem cell therapy is attractive. Through relatively simple and minimally invasive methods, physicians can harvest pluripotent cells…

Meeting News

Ixekizumab bests adalimumab in PsA in head-to-head comparison

June 13, 2019
Ixekizumab was associated with superior efficacy outcomes compared to adalimumab in a cohort of DMARD-naive patients with active psoriatic arthritis…

Feature Article

Despite the Safety of Preoperative Cefazolin for Patients With Non-anaphylactic Penicillin Allergy, 20% of Practitioners Avoid Its Use

Online Advanced Release, June 13, 2019
Cefazolin is commonly used for surgical site infection prophylaxis due to its low cost and effective coverage. However, it is controversial to use…

In the JournalsPerspective

No impact on safety, efficacy in etanercept-to-biosimilar switch in RA

June 12, 2019
Patients with moderate-to-severe rheumatoid arthritis who switch from etanercept to the biosimilar etanercept-szzs experienced no impacts on drug…

From OT Europe

RESTORE: A project on smart matrices for knee cartilage repair

Orthopaedics Today Europe, June 2019
A research project in cartilage regeneration was recently financed by the European Commission with 5.5 million euros. Named RESTORE…

Feature Article

Mechanisms of Suture Integration in Living Tissue: Biomechanical and Histological In Vivo Analysis in Sheep

Orthopedics, May/June 2019, Volume 42 Issue 3
The potential of nonabsorbable suture material to augment tissue strength in the long-term is by far not exploited by most of the currently used…

Meeting News

Medicare spending on DMARDs 'increased dramatically' over 4 years

May 1, 2019
DESTIN, Fla. — The amount of Medicare spending for conventional DMARDs used to treat rheumatoid arthritis ballooned from $98 million in 2012 to…

Trending in Orthopedics

The Role of Orthobiologics in the Management of Osteoarthritis and Focal Cartilage Defects

Orthopedics, March/April 2019, Volume 42 Issue 2
Individuals with osteoarthritis have a diminished quality of life, and the condition is a major cause of disability. Newer biologic treatments have…


What ACL graft is best for older active patients who are uncomfortable with receiving allograft tissue?

Orthopedics Today, March 2019
There is no question in my mind that the ideal ACL graft for an active older patient who is uncomfortable with an allograft is a quadrupled…

Cover Story

One approach does not fit all in ACL reconstruction

Orthopedics Today, March 2019
The ACL is reportedly one of the most commonly injured knee ligaments among professional- and recreational-level athletes, with a high risk for…

Meeting NewsVideo

VIDEO: Presenter discusses ways biologics may be incorporated into sports medicine

March 14, 2019
LAS VEGAS — At the American Academy of Orthopaedic Surgeons Annual Meeting, Brian J. Cole, MD, spoke about the use of orthopedic biologics in…

In the Journals

DMARD introduction coincides with decrease in upper limb joint replacement in RA

February 28, 2019
The incidence rate of upper limb joint replacements among patients with rheumatoid arthritis decreased from 2002 onward, coinciding with the…

From OT Europe

Sirakoss receives CE mark clearance for synthetic bone graft substitute

February 6, 2019
Sirakoss Ltd announced it received CE mark clearance for Osteo³, a nanosynthetic bone graft substitute intended to improve patient healing and…

Review Article

Accelerated Growth of Cellular Therapy Trials in Musculoskeletal Disorders: An Analysis of the NIH Clinical Trials Data Bank

Orthopedics, March/April 2019, Volume 42 Issue 2
The purpose of this study was to (1) determine the growth rate and the trends of musculoskeletal cellular therapy trials in the National Institutes…