Recently published data indicated a program of rehabilitation and platelet-rich plasma therapy may be more beneficial in patients with an acute hamstring injury than rehabilitation alone.
Researchers randomly assigned 28 patients who sustained an acute hamstring injury to single-injection autologous platelet-rich plasma (PRP) therapy and a rehabilitation program or to the rehabilitation program only. Return to play, pain interference scores and changes in pain levels were recorded.
A significant difference was observed in the time to return to play between the PRP cohort and the rehab-only cohort (26.7 vs. 42.5 days, respectively), according to the researchers. Full recovery was observed in 50% of the patients in the PRP cohort at the 26-week follow-up, compared with 39 weeks in the rehab-only cohort. Overall, patients in the PRP cohort were 4.8 times more likely to exhibit early return to play than those in the rehab-only cohort.
When taking into account age, duration of injury, length of injured area, active knee range of movement deficit and previous hamstring injury, administration of PRP therapy alone was determined to have a significant impact on return to play, according to the researchers.
Pain severity scores were also significantly lower in the PRP cohort than the rehab-only cohort.
Disclosure: This study was funded by the University of Malaya Research Grants (UMRG 382/11HTM) and the Institute of Postgraduate Studies (PV076/2011A).