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Bone marrow aspirate concentrate, hyaluronan-based scaffold effective for cartilage lesions in older patients

August 21, 2017

Read the Perspective from Bryan M. Saltzman, MD

Results from this study demonstrated bone marrow aspirate concentrate and a hyaluronan-based scaffold is viable and effective for the treatment of cartilage lesions, and its efficacy is not impacted by patient age.

Researchers compared 20 patients older than 45 years (study group) with 20 patients who were younger than 25 years (control group). All patients had full-thickness cartilage lesions of the knee joint and underwent cartilage implantation with bone marrow aspirate concentrate that was harvested from autologous, adult mesenchymal stem cells and placed on a hyaluronan-based scaffold. Investigators prospectively evaluated patients for 4 years. With MRI, KOOS, IDKC, VAS and Tegner scores, patients were assessed preoperatively and at the final follow-up.

In the JournalsPerspective

Bone wax seen as effective for decreasing total blood loss after TKA

July 31, 2017
Results from this study indicated that the use of bone wax in total knee arthroplasty safely and effectively reduced total blood loss and maintained hemoglobin levels…
Meeting News

Speaker lauds progress in cartilage repair field, but calls for more cost data, better diagnosis

July 24, 2017
TORONTO — More than 2 decades after a handful of promising new cartilage treatments were first used clinically, the field of cartilage repair is ready for new…
Meeting News

Majority of active patients returned to pretreatment function level after second-generation patellofemoral joint ACI

July 21, 2017
TORONTO — Investigators reported good success at about 2-years follow-up when they treated cartilage lesions sized 502 mm2 in the patellofemoral joint with a…
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Feature Article

BMP-7 Versus BMP-2 for the Treatment of Long Bone Nonunion

Orthopedics, December/January 2014, Volume 37 Issue 12
The authors compared the results of treating nonunion with either bone morphogenetic protein (BMP)-7 or BMP-2. Between…
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CME

Tissue Engineering Stratified Scaffolds for Articular Cartilage and Subchondral Bone Defects Repair

Due to their good biocompatibility and mechanical integrity, tissue engineering scaffolds have become a principal…
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Resource Centers
American Orthopaedic Society for Sports Medicine Annual Meeting

American Orthopaedic Society for Sports Medicine Annual Meeting

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Meeting News Coverage

Video: Freddie H. Fu, MD, DSc, DPs, discusses PRP for cartilage symptoms

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