Arthritis

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FDA: Limbrel linked to 'potentially life-threatening' problems

November 22, 2017

The FDA is investigating the drug Limbrel, a capsule-based product currently marketed as a medical food to manage the metabolic processes associated with osteoarthritis, for what the administration calls “serious adverse events.”

Limbrel (flavocoxid, Primus Pharmaceuticals) has been linked to a total of 194 of adverse events, including two “serious and potentially life-threatening” medical conditions — drug-induced liver injury and hypersensitivity pneumonitis — according to an FDA statement. Of the nearly 200 adverse events, 57 cases included sufficient information to determine whether there was a link to Limbrel, the administration said.

Meeting NewsVideo

VIDEO: Intra-articular sprifermin prevented cartilage loss in patients with knee OA

November 14, 2017
SAN DIEGO — At the American College of Rheumatology Annual Meeting, Marc C. Hochberg, MD, spoke about a study that evaluated the efficacy and safety of…
Meeting News

MRI reveals sacroiliac inflammation in both healthy runners, patients with spondyloarthritis

November 10, 2017
SAN DIEGO — Although sacroiliac MRI has been extensively relied on to diagnose axial spondyloarthritis, research presented at the American College of Rheumatology…
In the Journals

Multiple radiographic views increased detection of early OA

November 1, 2017
Use of different radiographic views appears to increase the frequency of radiographic osteoarthritis detection, according to results from the CHECK study. Researchers…
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Feature Article

Long-term Results of Shoulder Hemiarthroplasty in Patients With Rheumatoid Arthritis

Orthopedics, January/February 2015, Volume 38 Issue 1
Rheumatoid arthritis affecting the shoulder is typically associated with destruction of the glenohumeral joint and…
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CME

Effect of Topical Tranexamic Acid in Reducing Bleeding and Transfusions in TKA: May 2015

Intravenous tranexamic acid (TXA) has been identified to be effective in total knee arthroplasty (TKA), but the effect…
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Resource Centers
American Association of Hip and Knee Surgeons Annual Meeting

American Association of Hip and Knee Surgeons Annual Meeting

Video
Meeting News Coverage

VIDEO: Pelletier discusses glucosamine and chondroitin for patients with OA

March 1, 2016
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