An OCT integrated into an ultra-widefield device provides similar visualization of retinal structural details in eyes with disease compared to a standalone OCT device, according to a study presented at the Association for Research in Vision and Ophthalmology meeting.
Researchers utilized a prototype imaging device that combined ultra-widefield (UWF) scanning laser ophthalmoscopy (SLO) with OCT (Optos Inc.) to collect images from eyes with various retina pathologies including age-related macular degeneration, diabetic macular edema, diabetic retinopathy, macular holes and epiretinal membrane.
Comparison images were collected using a standalone SD-OCT (Optos Model E).
Thirty-five retina patients were imaged.
The researchers explained that the UWF SLO uses red and green lasers and captures retinal images extending out to 200 degrees, including the macula and far periphery. The SD-OCT in the new device scans at a rate of 70,000 A scans per second and covers an area up to 12 mm x 9 mm of the macula and optic disc.
The images were reviewed by two retina specialists.
Researchers also compared the visibility of two key structures used in reading center assessments of image quality, the external limiting membrane (ELM) and the choroid.
Disease features evident on the OCT B-scans included drusen, atrophy, pigment, epithelial detachment, cystoid macular edema, ellipsoid zone disruption, subretinal drusenoid deposits, nerve fiber thinning, vitreomacular traction and epiretinal membrane.
Researchers identified all features similarly between devices in all cases.
The ELM could be visualized in the line scan in 97% of the cases for both the UWF and OCT-only device, and the full extent of the choroid could also be seen in 69% of the cases with the UWF with OCT device and in 60% of the cases with the OCT-only device.
“The Monaco device provides the opportunity to obtain two different types of images in one sitting,” researcher Michael Singer, MD, told Primary Care Optometry News. “It also allows the clinician the ability to compare and analyze these images using the same platform. The Monaco also increases the efficiency of the office because both image types can be captured on the same machine without having to move the patient and slow down office flow.
“In addition, in difference disease types the Monaco was able to provide more insight because wide-field photography was able to capture disease that was not [detected] on OCT,” he added. – by Abigail Sutton
Gresores NJ, et al. Evaluation of a combined ultra-wide field SLO with SD OCT. Presented at: Association for Research in Vision and Ophthalmology; Honolulu; April 29-May 3, 2018.
Disclosures: Gresores reported no relevant financial disclosures. Singer reported receiving financial support from Aerpio, Alcon, Allergan, Allegro, Ampio, Clearside, Genentech, Guidepoint, Notal Vision, Ophthotech, Optos, Regeneron and Santen. Please see the full study for all remaining authors’ financial disclosures.