Researchers determined that the use of 24-hour IOP measurements obtained via a contact lens sensor were associated with the rate of visual field progression in patients undergoing treatment for glaucoma.
De Moraes and colleagues evaluated 34 patients between the ages of 40 and 89 years being treated for primary open-angle glaucoma and whose IOP measured 20 mm Hg or less. Patients had at least eight visual field tests performed within at least 2 years of follow-up.
Subjects wore the Sensimed Triggerfish wireless contact lens sensor and were evaluated for rates of visual field mean deviation change before and at the time of the IOP recording and the sensor parameters, including number of large peaks, mean peak ratio, wake-to-sleep slope, amplitude and area under the cosine curve, and variability from the mean, according to the study.
“When comparing the rate of mean deviation change before and at the time of contact lens sensor recording of all patients, the average slope was 0.05 dB/year faster in the beginning compared with the end (P = 0.087), suggesting a deceleration of progression by the time of contact lens sensor recording,” the researchers wrote. “The number of long peaks and the mean peak ratio when patients were awake were the best predictors of faster progression.”
They concluded that IOP parameters obtained with the 24-hour recording with the Triggerfish device were associated with the rate of visual field progression in these subjects.
“A combination of contact lens sensor parameters obtained during a single 24-hour session provides a signature that seems to explain the rate of glaucoma progression better than a summary of office-hour IOP measurements in multiple visits,” they said. – by Nancy Hemphill, ELS, FAAO
Disclosures: De Moraes is a consultant to Sensimed. Please see the full study for all authors’ financial disclosures.