September 19, 2017
Alberto Urrets-Zavalia first described Urrets-Zavalia syndrome in 1963 in patients with keratoconus who underwent penetrating keratoplasty. The patients developed a fixed dilated pupil after treatment with mydriatics. Since then, Urrets-Zavalia syndrome has been described after various intraocular surgeries such as deep anterior lamellar keratoplasty, Descemet’s stripping automated endothelial keratoplasty, phakic IOL placement, glaucoma surgeries and cataract removal. Postoperative rise in IOP is considered to be one of the factors responsible for fixed dilated pupils, probably due to involvement of the iris sphincter. It is also speculated that due to persistent pupil dilation the peripheral iris blocks the anterior chamber angle and leads to raised IOP.