Choroidal thickness was reduced in eyes with full-thickness macular holes and contralateral eyes with vitreomacular adhesion, according to a study.
The retrospective study included 19 patients with a unilateral full-thickness macular hole and contralateral vitreomacular adhesion. An age-matched control group comprised 19 healthy patients.
Three groups were analyzed: full-thickness macular hole, contralateral vitreomacular adhesion and controls.
Optical coherence tomography was used to measure choroidal thickness subfoveally and 1 mm and 2 mm away from the fovea in the nasal and temporal sectors.
Median subfoveal choroidal thickness was 197 µm in the full-thickness macular hole group, 215 µm in the contralateral vitreomacular adhesion group and 262 µm in the control group. The differences between the macular hole and vitreomacular adhesion groups and macular hole and control groups were statistically significant (P = .0013).
Differences in choroidal thickness were significant 1 mm nasal from the fovea between the macular hole and control groups and vitreomacular adhesion and control groups; 2 mm nasal from the fovea between the macular hole and control groups and vitreomacular adhesion and control groups; and 1 mm temporal from the fovea between the macular hole and control groups. There were no significant differences 2 mm temporal from the fovea.
The study authors said the findings suggest “an association between choroidal thinning and macular hole.”
Disclosure: See the study for a full list of all authors’ relevant financial disclosures.